moustafaaboelez

Moustafa O. Aboelez

Teadching-Assistant - مدرس مساعد -قسم الكيمياء الصيدلية

Faculty of Pharmacy

Address: سوهاج -مدينة ناصر -خلف المستشفي الجامعة -شارع نور الاسلام

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Welcome to my website page...I'm Moustafa omar aboelez , Assistant lecturer , Pharmaceutical Medicinal chemistry Department, Faculty of Pharmacy, Sohag University. I'm interested in Design, Synthesis and Biological Investigation. Please, tke a close look to my profile and I wish to be helpful for you

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2018-10-08 11:43:37
Free Research Editing Through the Egyptian Knowledge Bank
HOW TO REQUEST A FREE EDIT? -Note that you must be intending to publish your work in an international journal. -You can only receive 1 free edit per person, and your word count cannot exceed 6,000 words. * Firstly, get your request for editing approved by a dean at your institution. * Next, email to EKB copy editing department at ... Read more

2018-10-08 07:43:01
الذكري الخامسة والاربعين لحرب السادس من اكتوبر 
اتقدم بالتهنئة للشعب المصري الحبيب بمناسبة الذكري الخامسة والاربعين لحرب السادس من اكتوبر Read more

2018-10-01 06:08:14
طلابى الاعزاء
اهلا وسهلا بكم في موقعي الجامعي وكل عام وانتم بخير ،اتمني من طلابي الكرام متابعة الموقع بشكل دوري لمتابعة كل ماهو جديد .والتواصل ممايخدم العملية التعليمية Read more

DNA Interaction, Antimicrobial, Anticancer Activities and Molecular Docking Study of Some New VO(II), Cr (III), Mn(II) and Ni(II) Mononuclear Chelates encompassing Quaridentate imine ligand
The present study was conducted to synthesis of some new imine Cr(III), VO(II), Mn(II) and Ni(II) complexes derived from the condensation of 2-amino phenol with 2-hydroxynapthaldehyde were synthesized. The prepared HNPN imine ligand was analyzed by its melting point, IR, (1)H NMR and (13)C NMR spectroscopies. The investigated HNPN imine complexes were characterized by elemental analysis, FT IR, UV-vis and ... Read more

Efficient Protocol for the One-Pot Multicomponent Synthesis of Novel 2-Tosyloxyphenylpyrans and Schiff bases with Anti-inflammatory and Antioxidant Activities
1442One-PotMulticomponentSynthesisofNovel2-Tosyloxyphenylpyrans underGreenandConventionalConditionwithAnti-inflammatoryActivity Vol54 AhmedKhodairy, a AliM.Ali, a * MoustafaO.Aboelez, b andM.T.El-Wassimy a a DepartmentofOrganicChemistry,FacultyofScience,SohagUniversity,Sohag82524,Egypt b DepartmentofPharmaceuticalMedicinalChemistry,FacultyofPharmacy,SohagUniversity,Egypt *E-mail:elssan@yahoo.com AdditionalSupportingInformationmaybefoundintheonlineversionofthisarticle. ReceivedApril16,2016 DOI10.1002/jhet.2730 Publishedonline19July2016inWileyOnlineLibrary(wileyonlinelibrary.com). Amild,efficient,andenvironmentallygreenprotocolforthesynthesisof2-tosyloxyphenylpyran derivatives3-11viareactionof2-tosyloxybenzaldehyde(1)withmalononitrileandsomeketonicreagents inone-pot,threecomponentreactionwithinfewminutesunderstirringinmethanolinpresenceofammonium hydroxidesolutionorultrasonicirradiation.Ontheotherhand,thesameproducts3-11wereobtainedby traditionalmethod,ontreatmentof2-tosyloxybenzilidinemalononitrile(2)withthesameketonicreagents inrefluxingethanolinpresenceofTEA.2-Tosyloxyphenylpyranopyrazoles12and13wereobtainedvia treatmentofcompound1withmalononitrile,hydrazinehydrateorphenylhydrazineandethylacetoacetate, inone-pot,multicomponentreaction(MCRs).Thestructuresofthenewcompoundswereelucidatedbyele- mentalandspectralanalyses.Thenewlysynthesizedcompoundsshowedpromisinganti-inflammatoryactivity Read more

2018-09-12 21:42:04 | Keywords thiophenes, thienop, Pyridines,
SYNTHESIS, IN VITRO ANTIBACTERIAL AND IN VIVO ANTI-INFLAMMATORY ACTIVITY OF  NEW PYRIDINES
Reaction of 4,6-diamino-3-cyano-2-methylthiopyridine (I) with chloroacetyl chloride or acetic acid afforded the corresponding 6-acetamide derivatives IIa and IIb, respectively. Chloroacetamide derivative IIa reacted with various thiols, secondary amines, potassium thiocyanate, compounds containing active methylene group, 1-anilino-2,2-dicyanoethenethiolate, and o-mercatocyanopyridines to give S-alkyl, N-alkyl, thiazole, pyrrole, thiophene, and thienopyridine derivatives, respectively. Antibacterial and anti-inflammatory activities of some new pyridine derivatives were studied ... Read more

2018-09-12 21:48:55 | Keywords : 2-Tosyloxybenzaldehyde, 4-Tos, 2-Tosyloxybenzaldehyde, 4-Tosyl,
Design, Synthesis and Hypolipidemic Activity of Novel Hydrazones of Nicotinic acid Hydrazide
: Synthesis of novel N-acyl hydrazones of nicotinic acid hydrazide via condensation of nicotinic acid hydrazide 3 with the corresponding aldehydes 1, 2 are described. Their hypolipidemic activities were evaluated in high cholesterol diet fed rat model. The hydrazones were found to decrease the levels of serum total cholesterol, LDL cholesterol and triglycerides in hyperlipidemic rats to a greater degree ... Read more