_Background aims. _ Olfactory stem cells (OSCs) are found in the olfactory mucosa and olfactory bulb and have the capacity to proliferate and differentiate along multiple tissue lineages. Rotenone; widely used insecticide has a neurodegenerative effect on the dopaminergic cells of substantia nigra (SN) of midbrain producing Parkinsonism. The aim of this study is to isolate rat OSCs from olfactory ... إقراء المزيد

Olfactory stem cells (OSCs) are multipotent stem cells that can be isolated from the olfactory mucosa and olfactory bulb and have the capacity to proliferate when cultured on suitable media. Isolation of these cells helps to study their identity before being used as a cell therapy. THE AIM of this study is to isolate rat OSCs from olfactory mucosa and ... إقراء المزيد

_Background aims. _ Rotenone is a widely used insecticide has a neurodegenerative effect on the dopaminergic cells of substantia nigra (SN) of midbrain producing Parkinsonism. The aim of this study is to study the effects of rotenone when injected subcutaneously on the dopaminergic cells of the substantia nigra of the midbrain. _Methods_. The effects of rotenone on the SN of ... إقراء المزيد