Swallowed foreign bodies are common entity in our practice especially in children. Most ingested objects pass smoothly through the gastrointestinal tract or endoscopic ally removed. However, some patients experience undesirable outcomes We reported 3 cases under one year old (1 female, 2 males) brought to our ENT emergency by history of unusual ingested foreign body (Okra-pod); they were presented with ... Read more

Introduction Otomycosis is a common problem in otolaryngology practice. However, we usually encounter some difficulties in its treatment because many patients show resistance to antifungal agents, and present high recurrence rate. Objectives To determine the fungal pathogens that cause otomycosis as well as their susceptibility to the commonly used antifungal agents. Additionally, to discover the main reasons for antifungal resistance. ... Read more

Cholesteatoma is a proliferative disease of the middle ear with bone resorption activity. Its pathogenesis remains controversial and has yet to be clarified. Cytokeratins represent a well-known epithelial proliferative and differentiation markers. In the current study, we investigated expression of a large set of cytokeratins in cholesteatoma matrix versus deep meatal skin tissues from the same patients. Methodology: An immunohistochemical ... Read more

_OBJECTIVES_: To adopt a newly designed scoring/staging system for of tympanomastoid cholesteatoma similar to cancer staging protocols. _METHODS_: Our system relied on clinical, CT findings, and confirmed with intraoperative findings. All bony items that could be affected by cholesteatoma were scored, including: scutum (S), ossicles (O), mastoid (M), posterior canal wall (C), lateral sinus plate (L), inner ear (E), facial ... Read more

OBJECTIVES Cholesteatoma is a nonneoplastic destructive lesion of the temporal bone with debated pathogenesis and bone resorptive mechanism. Both molecular and cellular events chiefly master its activity. Continued research is necessary to clarify factors related to its aggressiveness. We aimed to investigate the expression of Ki-67, cytokeratin 13 (CK13) and cytokeratin 17 (CK17) in acquired nonrecurrent human cholesteatoma and correlate ... Read more

INTRODUCTION: Angiogenesis is an essential requirement for cholesteatoma growth and expansion. It is mediated via variety of cytokines and growth factors like basic fibroblast growth factor (basic-FGF). Localization of basic FGF in cholesteatoma matrix and its correlation with the destructive capacity of cholesteatoma were seldom seen in previous reports. METHODOLOGY: A prospective immunohistochemical study was employed using 19 acquired cholesteatoma ... Read more

We aimed to conduct a cross-sectional study in order to investigate the effect of periodic limb movements during sleep (PLMS) on daytime sleepiness in patients with sleep disordered breathing especially those with obstructive sleep apnea syndrome (OSAS), diagnosed by polysomnography (PSG). Our subjects included 233 male patients who visited our institute during the 25-month period between June 2012 and June ... Read more

Cholesteatoma is a cystic non tumorous lesion of the temporal bone that has the ability to destroy nearby structures by its power to cause bone resorption and as a result, fatal complications prevail. We aimed to conduct a comprehensive review for pathogenesis of acquired cholesteatoma, bone resorption mechanisms, and offer a future vision of this serious disease. We have reviewed ... Read more

Fibroepithelial pharyngeal polyps are rare. We herein report a case of a 56-year-old Asian woman who presented with voice hoarseness and throat discomfort for several years because of a giant pharyngeal polyp. We resected the polyp under general anesthesia. It originated in the left hypopharyngeal wall. Postoperative recovery was uneventful. Her sore throat was diminished within 1 week after the ... Read more

Objective. The aim of this study was to investigate the changes in velopharyngeal and glossopharyngeal airway morphology and volume after uvulopalatopharyngoplasty in three adult obstructive sleep apnea syndrome patients who had bilateral large tonsils using three-dimensional computed tomography. Case Report. All three patients (one male and two females) who presented with a history of heavy snoring and excessive daytime sleepiness ... Read more