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2018 | الكلمات المفتاحية breast cancer, Gene mutation, BRCA 1,
The Value of BRCA 1 Gene Mutation in Patients with Breast Cancer
_ABSTRACT_ INTRODUCTION: Breast cancer (BC) is the most common malignant tumor in females in almost all of countries with highest age-adjusted incidence in developed countries (73%) and includes the 23% of all types of cancers. World Health Organization (WHO) report shows that this prevalence rising 2% per year. As a matter of fact, BC is responsible for most of deaths ... إقراء المزيد

2018 | الكلمات المفتاحية breast cancer, CA 15-3,
Value of CA 15-3 in Female Patients with Breast Cancer
_ABSTRACT_ INTRODUCTION: Breast cancer (BC) is most common cancer site in women worldwide. The CA 15-3 is tumor associated antigen which detects soluble forms of MUC-1 protein. In normal breast tissue MUC-1 is expressed in the duct and acini, but with neoplastic transformation normal cell polarization and tissue architecture is disrupted leading to shedding of MUC-1 in the blood, where ... إقراء المزيد

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