fatmaelzahraa_ahmed

Dr. Fatma El-Zahraa Abdel-Hameed Abdel-Rahman Ahmed

Lecturer - Ph.D.

Faculty of science

Address: Zoology Department, Faculty of Science, Sohag 82524, Egypt

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2024 | Keywords FISH, Nanoparticles, Health in,
Dietary microalgal-fabricated selenium nanoparticles improve Nile tilapia biochemical indices, immune-related gene expression, and intestinal immunity
Background Feed supplements, including essential trace elements are believed to play an important role in augmenting fish immune response. In this context, selenium nanoparticles (SeNPs) in fish diets via a green biosynthesis strategy have attracted considerable interest. In this investigation, selenium nanoparticles (SeNPs, 79.26 nm) synthesized from the green microalga Pediastrum boryanum were incorporated into Nile tilapia diets to explore ... Read more

Self‑assembling Organogels Loaded with Tenoxicam for Local Intensive Pain and Inflammation Cure: In Vitro and In Vivo Correlation
Due to tenoxicam (TX)’s poor aqueous solubility (0.072 mg/ml), it is poorly absorbable in the GIT, and the long-term oral administration of TX may cause severe GIT disturbances. Topical administration of TX can help in bypassing the GIT adverse effects. Therefore, in the present work, we constructed different pluronic/lecithin organogels (PLOs) for topical delivery of TX. PLO was constructed simply ... Read more

2023 | Keywords AuNPs, Nanotechnology, drug de,
Recent Advances in the Pharmaceutical and Biomedical Applications of Cyclodextrin-Capped Gold Nanoparticles
The real problem in pharmaceutical preparation is drugs’ poor aqueous solubility, low permeability through biological membranes, and short biological t1/2. Conventional drug delivery systems are not able to overcome these problems. However, cyclodextrins (CDs) and their derivatives can solve these challenges. This article aims to summarize and review the history, properties, and different applications of cyclodextrins, especially the ability of ... Read more

2023 | Keywords Chitosan, Chitosan Nan, Dioxin,
Protective effect of chitosan and chitosan nanoparticles on dioxin induced haematotoxicity and nephrotoxicity in male albino rats
Chitosan (CH) is a natural product produced from the shells of crustaceans. Both CH and Chitosan nanoparticles (CHNPs) have recently been used in various pharmaceutical and biomedical applications. The present study aimed to evaluate the potency of chitosan or chitosan nanoparticles in reducing the negative effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)- induced haematotoxicity and nephrotoxicity in albino rats. Methods: Twenty adult male ... Read more

2023 | Keywords His, FISH, fatty acids, growth,
Nutritional and immunological evaluation of Nannochloropsis oculata as a potential Nile tilapia-aquafeed supplement.
_Nannochloropsis oculata_ (_N. oculata_) is a marine microalga containing bioactive compounds and a high omega-3 polyunsaturated fatty acid (ω-3 PUFAs). Therefore, it is very promising for nutraceutical and the functional food industry applications. Three groups of Nile tilapia (forty-five fish/group) were fed on basal diets or diets containing 5% (N5) or 10% (N10) of the microalga _N. oculata_ for seven ... Read more

Smart Injectable Chitosan Hydrogels Loaded with 5-Fluorouracil for the Treatment of Breast Cancer
The treatment of breast cancer requires long chemotherapy management, which is accompanied by severe side effects. Localized delivery of anticancer drugs helps to increase the drug concentration at the site of action and overcome such a problem. In the present study, chitosan hydrogel was prepared for local delivery of 5-Fluorouracil. The in vitro release behavior was investigated and the anticancer ... Read more

Therapeutic Intervention with Dietary Chitosan Nanoparticles Alleviates Fish Pathological and Molecular Systemic Inflammatory Responses against Infections
Marine bio-sourced chitosan nanoparticles (CSNP) are antimicrobial and immunomodulatory agents beneficial for fish medicine. Herein, dietary CSNP was investigated for the amelioration of the systemic inflammatory responses of an induced fish model. One hundred and forty-four rainbow trout were assigned to one pathogen-free and non-supplemented group (negative control), and three challenged groups: non-supplemented (positive control), CSNP-preventive, and CSNP-therapeutic. After a ... Read more

2022 | Keywords
Interactive effects of dietary betaine and chromium picolinate on the immunomodulation, antioxidative response and disease resistance of Nile tilapia (Oreochromis niloticus)
Fish feed additives are recently encouraged to improve cultured fish health and production. Dietary supplementation with betaine (Bet) and chromium picolinate (Cr-Pic) is known for its high quality for the benefit of aquaculture. A total of 180 healthy and equal-sized O. niloticus were fed on a non-supplemented basal diet, or a basal diet supplemented with Bet (10g/kg dry feed) (Bet ... Read more

Fish’s Crustacean Parasites: Types, Prevalence, Clinical signs, and Control
Crustaceans during a parasitism relationship with fish cause biological disruption and diseases to the hosting fish that threaten their life. Several crustacean groups were reported to parasitize different fish species as definitive hosts. Copepods, Isopods, and Branchiura are the major fish parasitic groups under the crustacea. They are mainly ectoparasites and occasionally, the small and microscopic members can infest the ... Read more

Toxicity Evaluation, Oxidative, and Immune Responses of Mercury  on Nile Tilapia: Modulatory Role of Dietary Nannochloropsis oculata
The current study evaluated the potential ameliorative effect of a dietary immune modulator, Nannochloropsis oculata microalga, on the mercuric chloride (HgCl2)-induced toxicity of Nile tilapia. Nile tilapia (45–50 g) were fed a control diet or exposed to ¼ LC50 of HgCl2 (0.3 mg/L) and fed on a medicated feed supplemented with N. oculata (5% and 10% (50 or 100 g/kg ... Read more