essameldin_nada

Essameldin Abdelaziz Mohamed Ahmed Nada

Professor - Prof. of Dermatology,Venereology and Andrology

Faculty of medicine

Address: 8 Abou Bakr ElSedik Dokki Giza

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Role of Nerve Growth Factor (NGF) and Its Receptor Tyrosine Kinase A (TrK A) in Egyptian Cirrhotic Patients with Pruritus.
Background: Pruritus is a distressing symptom of cholestatic, inflammatory,and malignant liver diseases. It is a common symptom in many biliary andcholestatic disorders such as primary biliary cirrhosis (PBC). Several mechanisms are generally accepted as possible explanations to the underlying basis of itch.However, the exact pathophysiology of pruritus in liver diseases remains unclear.The cutaneous and central neurobiology of pruritus is complex ... Read more

Lesional and circulating levels of interleukin‐17 and 25‐ hydroxycholecalciferol  in active acne vulgaris: Correlation to disease  severity
OBJECTIVES: The immunological aspects of inflammatory acne are still incompletely understood, so this study aimed to investigate the possible role of IL‐17 and 25 hydroxycholecalciferol (25(OH)D3) in the disease pathogenesis and progression. MATERIALS AND METHODS: Across‐sectional study has been conducted on 135 patients with active acne vulgaris of various severities and 150 matched controls. ELISA assays of serum and tissue ... Read more

Efficacy of microneedling with topical vitamin C in the treatment of melasma.
Summary Background: Despite the wide therapeutic options available for the treatment of me‐ lasma, including many active topical medications, technologies with lights and peel‐ ings, clinical control of this disorder is extremely challenging. Objectives: To evaluate the effect of microneedling with topical vitamin C in the treatment of melasma. Methods: Thirty female patients with melasma received six sessions of micronee‐ ... Read more

Epidemiologic Trends of Viral Skin Infections in  Egypt: A Cross-Sectional Hospital-Based Study.
Viral skin infections (VSIs) were ranked among the top 50 prevalent diseases in 2010. The objective of this study was to determine the epidemiologic features of VSIs in patients attending a dermatology clinic in Egypt from June 2010 to May 2011. Patient’s residence, occupation, housing data, and family history of similar conditions were recorded. Categorical data were recorded as frequencies ... Read more

Efficacy  of  sildenafil  citrate  in  the  treatment  of  female  sexual dysfunction.
INTRODUCTION: Female sexual dysfunction (FSD) defines as disturbances in the female sexual response cycle resulting in marked distress and interpersonal difficulties. Sildenafil citrate was effective in treatment of FSD through increasing blood flow to corpus cavernosum of clitoris, vagina and labia minor. AIM:To evaluate the effect of sildenafil citrate in treatment of female sexual dysfunction. PATIENTS AND METHODS: An observational ... Read more

Fractional Erbium-YAG Laser and Platelet-Rich Plasma as Single or Combined Treatment for Atrophic Acne Scars: a Randomized Clinical Trial.
Introduction: Acne scarring is a common undesirable complication of acne vulgaris. Fractional erbium-yttrium aluminum garnet (YAG) 2940 nm laser and platelet-rich plasmahave been used in treating acne scars with variable outcomes. The objective of this study is to assess the efficacy of fractional erbium-YAG 2940 nm laser and platelet-rich plasma as single line of treatment in comparison with combined treatment ... Read more

Intralesional injection of vitamin D3 versus zinc sulfate 2% in treatment of plantar warts: a comparative study.
BACKGROUND: Plantar warts are common skin lesions caused by the human papilloma virus. It is characterized by presence of a horny ring of hyperkeratosis surrounding the wart, making its elimination a therapeutic challenge. Several destructive agents are available for treatment with variable success. Intralesional vitamin D3 has been reported a successful treatment of warts. Intralesional zinc sulfate has been found ... Read more

Comparative study of the immunological profile in stable segmental and non-segmental Vitiligo patients undergoing melanocyte keratinocyte transplantation.
Vitiligo is an acquired autoimmune depigmentation of the skin, affecting 2%of the population with great impact on quality of life, which is more devastating in people with skin of color. The most important selection criterion in vitiligo for considering melanocyte keratinocyte transplantation procedure (MKTP) is stability. However, there is no consensus regarding the required period to define clinical stability. Moreover, ... Read more

Leptin concentration in seminal plasma of infertile men and relationship to semen parameters and some hormonal levels.
Introduction: Leptin is a 167 - amino acid polypeptide hormone, identified in 1994 by positional cloning in the mouse and human. This hormone is secreted by the white adipose tissue in proportion to body energy (fat) stored. Leptin functions as a satiety factor in the regulation of body weight. So far, many studies have pointed to a direct role of ... Read more

2018 | Keywords leprosy, interleukin-6, INTERFERON-γ,
Serum interleukin-6 and interferon-γ in patients with  leprosy.
Background Leprosy is a chronic infectious disease caused by Mycobacterium leprae and manifested by an immunological and clinical outcome, ranging from borderline lepromatous and lepromatous infections to tuberculoid and borderline tuberculoid infections. Cytokines such as interleukin (IL)-6, IL-10, interferon-γ (IFN-γ), and tumor necrosis factor-α are associated with leprosy. Objective The aim was to assess IL-6 and IFN-γ in untreated patients ... Read more