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Objectives: This study aims to assess simple models from routine investigation for prediction of significant fibrosis (Ishak score > 2) and cirrhosis in CHC patients. Patients and Method: Our retrospective cohort study studied 100 chronic HCV patients that had liver biopsy. Two indices were assessed, aspartate aminotransferase platelets ratio index (APRI) and FIB-4 to predict significant fibrosis and cirrhosis. Result: ... Read more

BACKGROUND/AIMS: To evaluate the incidence, risk factors of RF among cirrhotic and its impact on patient’s outcome. MATERIALS AND METHODS: A total of 573 cirrhotic patients were evaluated for renal failure (RF) and its causes, 212 patients (37%) were enrolled. RESULTS: Majority of the patients had post hepatitis C liver disease (n=190, 89.6%) with Child-Pugh score C (88.2%), HCC was ... Read more

BACKGROUND/AIMS: Variceal bleeding is one of the most frequent causes of morbidity and mortality among cirrhotic patients. Clinical endoscopic features and outcomes of cirrhotic patients with non-variceal upper gastrointestinal bleeding (NVUGIB) have been rarely reported. Our aim is to identify treatment outcomes and predictors of in-hospital mortality among cirrhotic patients with non-variceal bleeding in Upper Egypt. MATERIALS AND METHODS: A ... Read more

INTRODUCTION: Differential diagnosis of ascites is a common clinical problem. AIM OF THE WORK: To study the value of Serum Ascites Lipid Gradients (SALG) of total cholesterol, triglyceride, HDL cholesterol, and LDL cholesterol in the diagnosis of ascites. MATERIALS AND METHODS: The study was conducted on patients with ascites admitted to Tropical Medicine and Gastroenterology Department, Assiut University. The study ... Read more

BACKGROUND: Vertical transmission of hepatitis B virus (HBV) is known to be the most common cause of peri-natal infection. THE PURPOSE OF THE WORK: To demonstrate the prevalence, possible risk factors of HBV infection among pregnant women in Upper Egypt, and target women for post partum immunization. PATIENTS AND METHODS: 294 pregnant Egyptian women were consecutively recruited from outpatients' clinic ... Read more

Background :Spontaneous bacterial empyema (SBEM) is a complication in cirrhotic patients, in which a preexisting pleural effusion becomes infected. Purpose: The purpose was to determine the prevalence and causative organisms of SBEM among cirrhotic patients with hydrothorax. Materials and methods: This descriptive, cross-sectional study included 901 cirrhotic patients. All patients underwent clinical evaluation, liver function tests, chest X-ray, abdominal and ... Read more

Background/aim:An impaired lipid metabolism is often observed in patients with chronic liver diseases. This study was carried out to determine the lipid profile in cirrhotic patients with and without hepatocellular carcinoma (HCC) and to determine whether it relates to the severity of cirrhosis in Upper Egypt. Patients and methods In an analytical cross-sectional study, 74 patients with cirrhosis and 36 ... Read more

Background and study aims: Association of ulcerative colitis (UC) with hepatobiliary disorders is well recognised. The most common hepatobiliary complications of inflammatory bowel disease (IBD) are fatty liver infiltration and cholelithiasis. The prevalence of liver dysfunction in IBD remains unclear. The aim of the study is to try to identify the frequency and risk factors of hepatobiliary disorders among patients ... Read more

Background and study aims: Renal dysfunction is a common and serious problem in patients with advanced liver disease. The study aims to assess the incidence, risk factors and short-term prognosis of renal failure after upper-gastrointestinal bleeding among cirrhotic patients in Upper Egypt. Methods: We recruited 159 cirrhotic patients with 168 episodes of upper-gastrointestinal bleeding from Tropical Medicine and Gastroenterology Department, ... Read more