khairy.hamam576

Khairy Hammam Morsy

Professor - Professor of Tropical Medicine and Gastroenterology

Faculty of medicine

Address: Sohag, Egypt

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| Keywords Gut microbiota, CRC,
Interplay between Gut Microbiota and T Lymphocytes in Colorectal Cancer
Colorectal cancer is one of the third leading causes of cancer mortality worldwide. There is increasing evidences about the involvement of gut microbiota in colorectal carcinogenesis. Several recent studies have shed light on the cross talk between gut microbiota and mucosal T cell subsets, specically intraepithelial lymphocytes and lamina propria CD4+ T cells including T-helper cells and T- regulatory (Treg) ... Read more

| Keywords IL17a,
Serum Level of IL17a among Cirrhotic Hepatitis C Virus Infected Patients with Incidence of Diabetes Mellitus.
IL17a is the key inflammatory cytokine of TH17 and contributes to the pathogenesis of diabetes mellitus which is a common endocrine disorder associated with HCV infection. Herein, 183 cirrhotic HCV infected patients were screened for ANA by ELISA and positive cases (n=40) were screened for ICA by Immunofluorescence and IL17a serum levels were measured by ELISA and compared to a ... Read more

| Keywords Variceal bleeding,
Scoring Systems and Risk Stratification in Cirrhotic Patients with Acute Variceal Bleeding "Scoring in Variceal Bleeding"
OBJECTIVES: To find the most accurate, suitable and applicable scoring system used for prediction of outcome in cirrhoticpatients with bleeding varices. METHODS: This prospective study included 120 cirrhotic patients with acute variceal bleeding, admitted at Department of Tropical Medicine and Gastroenterology in Sohag University Hospital over a one-year period (1/2015 to 1/2016). Clinical, laboratory and endoscopic parameters were studied, Child–Pugh ... Read more

Wandering spleen in the pelvic region in an adult man with symptoms of acute abdomen.
Wandering or ectopic spleen is a condition characterised by migration of spleen in the abdomen or pelvis. This anomaly is rare, with a reported incidence of Read more

| Keywords Variceal bleeding,
Variceal bleeding in cirrhotic patients: What is the best prognostic score?
BACKGROUND/AIMS: To find the most accurate, suitable, and applicable scoring system for the prediction of outcome in cirrhotic patients with bleeding varices. MATERIALS AND METHODS: A prospective study was conducted comprising 120 cirrhotic patients with acute variceal bleeding who were admitted to Tropical Medicine and Gastroenterology Department in Sohag University Hospital, over a 1-year period (1/2015 to 1/2016). The clinical, ... Read more

Efficacy of ombitasvir/paritaprevir/ritonavir/ribavirin in management of HCV genotype 4 and end-stage kidney disease
BACKGROUND Till now, pooled data about the safety and efficacy of different direct-acting antiviral(DAAs) regimens in different renal situations are still under evaluation. AIM To evaluate a real-life experience of the efficacy and safety of ombitasvir/paritaprevir/ritonavir plus ribavirin (OBV/PTV/r plus RIB) in patients with end-stage kidney disease (ESKD). PATIENTS AND METHODS Between January 2017 and January 2018, an open-label multicenter ... Read more

| Keywords PCR,
Clinical, laboratory, and virological characteristics of patients with positive hepatitis B surface antigen in Upper Egypt
AIM The aim of the study was to determine the clinical, laboratory, and virological characteristics of patients with chronic HBV infection in Upper Egypt. PATIENTS AND METHODS This descriptive, cross-sectional study included 252 patients with positive hepatitis B surface antigen (HBsAg). It was conducted in the Tropical Medicine and Gastroenterology Department and Outpatient Clinic, Assiut University Hospital (Egypt), from May ... Read more

| Keywords HCV,
Can eicosapentaenoic acid maintain the original ribavirin dose or affect the response during the treatment course of chronic hepatitis C virus (HCV) patients?
BACKGROUND/AIMS: Combination therapy with peginterferon (PEG-IFN) and ribavirin (RBV) has been recommended as a standard therapy for patients with chronic hepatitis C virus (HCV). Our aim was to evaluate the efficacy of eicosapentaenoic acid (EPA) against RBV-associated hemolytic anemia. MATERIALS AND METHODS: Two hundred and forty HCV patients included in the study were randomized to either the EPA group (n=120) ... Read more