usama_morssy

Usama Ahmed Arafa Morsy

Professor - Head of Internal Medicine Department

Faculty of medicine

Address: شارع خلف الاستاد ، مدينة ناصر، سوهاج ثان ، سوهاج

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Telomere Dysfunction-Related Serological Markers in Patients with Type 2 Diabetes: Correlation with Methylene Tetrahydofolate Reductase (C677T) Gene Polymorphism and Diabetic Complications
OBJECTIVE: Recent studies have identified a set of serological markers for telomere dysfunction and DNA damage. In the present study, the levels of 2 serological markers of telomere dysfunction namely chitinase and N-acetylglucosaminidase (NAG) were studied in type 2 diabetes mellitus (T2DM) patients. The possibility that genomic damage, accumulation of reactive oxygen species and shorter telomeres may be linked to ... Read more

Effects of Oral L-Carnitine on Liver Functions after Transarterial Chemoembolization in Intermediate-Stage HCC Patients
BACKGROUND/AIM: Transarterial chemoembolization (TACE) is usually followed by hepatic dysfunction. We evaluated the effects of L-carnitine on post-TACE impaired liver functions. METHODS: 53 cirrhotic hepatocellular carcinoma patients at Osaka Medical College were enrolled in this study and assigned into either L-carnitine group receiving 600 mg oral L-carnitine daily or control group. Liver functions were evaluated at pre-TACE and 1, 4, ... Read more

Angiotensin-Converting Enzyme and its Gene Polymorphism (I/D) in Essential Arterial Hypertension
BACKGROUND/AIM: Few studies were performed to examine the linkage between ACE gene I/D polymorphism and essential hypertension with conflicting results. Therefore, we carried out this study to determine if this polymorphism was associated with an altered risk of hypertension and its relation to serum ACE in a sector of Egyptian population. PATIENTS AND METHODS: Sixty-eight normotensive subjects and 66 hypertensive ... Read more

Blue Mode Imaging may Improve the Detection and Visualization of Small Bowel Lesions: A Capsule Endoscopy Study
BACKGROUND/AIMS: Diagnostic miss rate and time consumption are the two challenging limitations of small‑bowel capsule endoscopy (SBCE). In this study, we aimed to know whether using of the blue mode (BM) combined with QuickView (QV) at a high reviewing speed could influence SBCE interpretation and accuracy. MATERIALS AND METHODS: Seventy CE procedures were totally reviewed in 4 different ways; (1) ... Read more

Role of Dobutamine Stress Echocardiography in the Evaluation of Coronary Ischemia in Diabetic Patients Before and After Coronary Revascularization In Upper Egypt
INTRODUCTION: CARDIOVASCULAR DISEASES ARE CONSIDERED THE LEADING CAUSE OF DEATH IN PATIENTS WITH DIABETES IN PARTICULAR, CORONARY ARTERY DISEASE (CAD) IS THE CAUSE OF DEATH IN MORE THAN HALF OF THESE PATIENTS. DIABETES IS PRESENT IN AS MANY AS 30% OF PATIENTS HOSPITALIZED BECAUSE OF ACUTE CORONARY SYNDROMES AND IS ASSOCIATED WITH GREATER MORTALITY DURING THE ACUTE PHASE OF MYOCARDIAL ... Read more

Transforming Growth Factor-β1 in Patients with Chronic Hepatitis B Virus Infection
BACKGROUND: The transforming growth factor-β1 (TGF-β1) is an important cytokine with anti-inflammatory properties and may have a role in the pathogenesis of liver fibrosis. OBJECTIVES: The main purpose of this study was to compare serum levels of TGF-β1 in a group of chronic hepatitis B (CHB) patients as well as healthy individuals and to determine the correlation between the TGF-β1 ... Read more

Predictors of Bleeding from Esophageal Varices: The Role of Factor VII and von Willebrand Factor (vWF)
OBJECTIVES: Bleeding from gastroesophageal varices is the most serious and life-threatening complication of cirrhosis and accounts for 10% of all cases of bleeding from the upper gastrointestinal tract. It is essential to identify and treat those patients at the highest risk because each episode of variceal hemorrhage carries a 20% to 30% risk of death, and up to 70% of ... Read more

Serum Leptin, Ferritin and Uric Acid as Predictors of Fibrosis and Sustained Virological Response in Chronic Hepatitis C Patients
Hyperleptinemia, hyperferritinemia and hyperuricemia have been implicated in hepatic inflammation and fibrosis and assumed to be predictors of poor response to antiviral therapy. The aim of study was to evaluate the role of serum leptin, ferritin and uric acid in progression of chronic hepatitis C (CHC) disease and their role in detection of virological response to combined antiviral therapy (pegylated ... Read more

The Association between Hepatitis C Virus Infection and Lymphoma
OBJECTIVES: To identify the frequency of HCV infection among patients with Non-Hodgkin’s lymphoma (NHL) and Hodgkin’s disease (HD). SUBJECTS AND METHODS: The study involved 152 patients; 111 with NHL and 41 with HD proved by lymph node biopsy and a control group of 50 individuals attending the internal medicine outpatient clinic of Sohag University hospital. ELISA technique was used for ... Read more

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