hasnaa_aboalwafa

Hasnaa Ahmed Aboelwafa

Professor - Prof. of Clinical Pathology - Head of clinical pathology department

Faculty of medicine

Address: Sohag University Hospital , Clinical Pathology Department

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2018 | Keywords aberrant, LEUKEMIA, CD Markers,
Aberrant Expression of CD Markers in Cases with Acute Leukemia in Sohag University Hospital
INTRODUCTION: Acute leukemias are a group of malignancies with clinical, morphologic, immunologic, and molecular patterns and display patterns of surface antigen expression (CD antigens). Precursor cells from different blast cells in acute leukemia express different subdivisions of surface molecules many of which are now defined as cluster of differentiation (CD) antigens. Every leukemia type has specific set of CD markers, ... Read more

2018 | Keywords CLL, CD39,
CD39 Expression on T Lymphocytes Correlates With Severity  of Disease in Patients With Chronic   lymphocytic leukemia
Chronic lymphoid leukemia (CLL), is the most common type of leukemia (a type of cancer of the white blood cells) in adults representing 25%-30% of all leukemias, CLL is a disease of adults. Most (>75%) people newly diagnosed with CLL are over the age of 50, and the majority are men, The leukemia is characterized by a clonal expansion of ... Read more

2018 | Keywords stem cell therapy,
Stem Cell Therapy
INTRODUCTION: Stem cells have an interesting history, it traces from mid of 1800 to the date, and it remains the most controversial issue of research even today. The ability of stem cells to self-renew and give rise to generations with variable degrees of differentiation capacities, offers significant potential for generation of tissues that can replace diseased and damaged ones. AIM ... Read more

2018 | Keywords Philadelphia Chromosome ALL,
Philadelphia Chromosome In Acute Lymphoblastic Leukemia
ABSTRACT BACKGROUND. Acute lymphoblastic leukemia (ALL) is a malignant disease of the bone marrow in which early lymphoid precursors proliferate and replace the normal hematopoietic cells of the marrow. Philadelphia chromosome (Ph)-positive ALL, a high-risk cytogenetic subset, accounts for 25-30% of adult ALL cases but occurs in less than 5% of children. We aimed with this study to detect Ph ... Read more

2018 | Keywords CD36-Acute leukemia,
: CD36  in Acute Myeloid Leukemia in Correlation to Blood Picture and Clinical Variables  Hasnaa A Abo-Elwafa, Mohammed A Mohammed, Ahmed A Allam and   Ahmed M Sayed  Clinical Pathology Department, Sohag Faculty of Medicine, Sohag University, Egypt
TITLE: CD36 IN ACUTE MYELOID LEUKEMIA IN CORRELATION TO BLOOD PICTURE AND CLINICAL VARIABLES Hasnaa A Abo-Elwafa, Mohammed A Mohammed, Ahmed A Allam and Ahmed M Sayed Clinical Pathology Department, Sohag Faculty of Medicine, Sohag University, Egypt AUTHORS AFFILIATIONS: 1- Hasnaa Ahmed Abo- Elwafa Corresponding author Hasnaa_aboalwafa@med.sohag.edu.eg Assistant Prof. of Clinical Pathology Sohag Faculty of Medicine, Sohag University, Egypt 2-Mohammed ... Read more

2018 | Keywords Keywords CD85k, Monocytic Line,
Surrogate Role of CD85k on Monocytic Lineage Involved Leukemogenesis Biology and Clinical Aspect
SURROGATE ROLE OF CD85K ON MONOCYTIC LINEAGE INVOLVED LEUKEMOGENESIS BIOLOGY AND CLINICAL ASPECTHasnaa A Abo-Elwafa1, Heba A E Ahmed1, Elsayed M Ali2, Doaa S Elsaied1, and Azyzi P S 1Clinical Pathology Department1and Clinical Oncology Department, Sohag Faculty of Medicine, Sohag University, EgyptCorresponding author: Hasnaa Ahmed Abo-ElwafaAssistant Prof. of Clinical Pathology, Faculty of Medicine, Sohag University, EgyptHasnaa_aboalwafa@med.sohag.edu.eg Open Journal of Blood ... Read more

2018 | Keywords breast cancer, CA 15-3,
Value of CA 15-3 in Female Patients with Breast Cancer
INTRODUCTION: Breast cancer (BC) is most common cancer site in women worldwide. The CA 15-3 is tumor associated antigen which detects soluble forms of MUC-1 protein. In normal breast tissue MUC-1 is expressed in the duct and acini, but with neoplastic transformation normal cell polarization and tissue architecture is disrupted leading to shedding of MUC-1 in the blood, where it ... Read more

The Value of BRCA 1 Gene Mutation in Patients with Breast Cancer
INTRODUCTION: Breast cancer (BC) is the most common malignant tumor in females in almost all of countries with highest age-adjusted incidence in developed countries (73%) and includes the 23% of all types of cancers. World Health Organization (WHO) report shows that this prevalence rising 2% per year. As a matter of fact, BC is responsible for most of deaths due ... Read more

2017 | Keywords Temperature Storage Duration,
Influence of Temperature And Storage Duration on Measurement of Prothrombin Time.
OBJECTIVES:toinvestigate the sample stabilitywith regard to the temperatureand the storage time and to detect influence of temperature and storage duration on Prothrombin time in citrated plasma. PATIENTS AND METHOD:This study was carried out in the period between April, 2016 and March, 2017 in the department of clinical pathology, Sohag University Hospital, Sohag, Egypt, during the study period whole blood samples ... Read more

2017 | Keywords Lymphoprolofrative, ILT3,
Expression of ILT 3 in Clonal Lymphoproliferative Disorders
B-cell chronic lymphocytic leukemia (B-CLL), also known as chronic lymphoid leukemia (CLL), is the most common type of leukemia (a type of cancer of the white blood cells) in adults, CLL affects B cell lymphocytes,Immunoglobulin-like transcript-3 (ILT-3), a member of the immunoglobulin superfamily, is a transmembrane inhibitory receptor expressed on antigen-presenting cells (APCs) such as monocytes and dendritic cells (DCs) ... Read more