hekmat_osman

hekmat_osman

Professor -

Faculty of medicine

Address: كلية طب جامعة سوهاج

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2019 | Keywords periostin stem cell,
Periostin expression and characters of human adipose tissue-derived mesenchymal stromal cells were aberrantly affected by in vitro cultivation
Background: Human adipose tissue-derived mesenchymal stromal cells (AD-MSCs) have been under focus in regenerative medicine since their discovery as a suitable source of MSCs. AD-MSCs are heterogeneous cells and exhibit variations in population doubling time, morphology and proliferative capacity. This study investigated if human AD-MSCs are developing, during in vitro long-term cultivation, in an unwanted or aberrant way. Methods: This ... Read more

2018 | Keywords Histochemical, liver,
Ultrastructural, histochemical and biochemical effects of titanium dioxide nanoparticles on adult male albino rat liver and possible prophylactic effects of milk thistle seeds
Titanium dioxide nanoparticles (Tio2 NPs) are manufactured worldwide in large quantities for use in a wide range of applications. TiO2 NPs proved to damage liver function and induce an oxidative stress attack leading to liver toxicity. Milk thistle is an herbal supplement used to treat liver and biliary disorders. Silymarin, an active ingredient of milk thistle, is a strong antioxidant ... Read more

2018 | Keywords
Oxytocin versus Alendronate in Treating Postmenopausal Osteoporotic Female Rats; Which is Better?
Background: post menopausal period is a critical period for each female. How to minimize the complications of this period is a matter of major concern. Materials and Methods: 40 females' albino rates were included in this study; they were divided into four equal groups. G1: Sham ovariectomized group, G2: ovariectomized group receiving vehicle (Ve) 1mg/kg/day for 7 weeks intraperitoneal injection ... Read more

2017 | Keywords
METHOTREXATE INHIBITS RANKL INDUCED OSTEOCLASTOGENESIS OF HAEMOPOEITIC STEM CELLS HISTOLOGICAL AND MOLECULAR BIOLOGY STUDY
osteoclastogenesis of mouse bone marrow macrophages can be used as stem cell research to study the effect of some drugs Read more

2016 | Keywords antioxidant enzymes, Cartilage,
STRONTIUM RANELATE AS A NEW TREATMENT OF KNEE OSTEOARTHRITIS INDUCED BY MONOSODIUM IODOACETATE IN ALBINO RATS
To evaluate the efficacy the possible mechanism of action of strontium ranelate (SR) in the treatment of knee OA induced by mono-sodium-iodoacetate (MIA) as a new indication of this drug, also, to detect whether cartilage oligomeric matrix protein (COMP) is a reliable biomarker that can facilitate the diagnosis of osteoarthritis (OA). METHODS: twenty-four adult male _Swiss_ albino rats weighing 150–200 ... Read more

2015 | Keywords
Histological Effects of Titanium Dioxide Nanoparticles in Adult Male Albino Rat Liver and Possible Prophylactic Effects of Milk Thistle Seeds
Abstract: Titanium dioxide nanoparticles (TiO2 NPs) are manufactured worldwide in large quantities for use in a wide range of applications including pigment, plastics, papers, inks, food colorants, toothpastes and cosmetic manufacturing. Milk thistle is a herbal supplement used to treat liver and biliary disorders. Silymarin, an active ingredient of Milk thistle, is a strong antioxidant that promotes liver cell regeneration ... Read more

2013 | Keywords aflatoxicosis. Lung pathology, ,
Lung toxicity in experimentally induced aflatoxicosis
AIM OF THE WORK: THE STUDY WAS DONE TO SEE THE EFFECTS OF EXPERIMENTAL AFLATOXICOSIS ON THE HISTOLOGICAL STRUCTURE OF THE LUNG OF ADULT FEMALE ALBINO RATS MTERIIALS AND METHODS: SIXTY FOUR ADULT FEMALE ALBINO RATS WERE DIVIDED INTO FOUR EQUAL GROUPS.EACH OF THESE GROUPS WAS SUBDIVIDED INTO FOUR SUBGROUPS. SUBGROUP A WAS THE CONTROL. SUBGROUP B RECEIVED 1.65 ML ... Read more

2012 | Keywords CCl4, ginger, pars distalis, P,
Ultrastructural study of the effect of carbon tetrachloride on the pars distalis of the anterior pituitary gland of mice and the possible protective role of ginger
Free radicals and oxidative stress can be induced by a variety of factors, such as carbon tetrachloride (CCl4). Ginger (Zingiber officinale Roscoe, Ginger) has antioxidant, antitumoral, and antihepatotoxic activities. Aim of the work The present study was carried out to assess the possible role of ginger on CCl4- induced toxic effects on the pars distalis. Materials and methods Thirty adult ... Read more

2012 | Keywords aflatoxin-B1 -ovary,
Effect of aflatoxin-B1 on the ovary of female rats and its role in reproductive disabilities
Aflatoxin contamination of foods is a well known problem, especially in developing countries. Aflatoxins also have been suspected to reduce human fertility AIM OF THE STUDY: to study the effect of aflatoxin B1 on the histological structure of the ovary in female rats. MATERIALS AND METHODS: eighty healthy adult female rats (Whister strain) were divided into four groups, 20 rats ... Read more

The possible protective role of curcumin on the toxic effect of nicotine in the lung of adult male mice: histological study
INTRODUCTION Nicotine is an alkaloid that was responsible for most of the dangerous effects of cigarette smoking on human body health. Curcumin is a component of turmeric that is a yellow spice derived from the plant curcuma longa and has anti-inflammatory, antioxidant and antimalignancy properties. AIM OF THE WORK: Is to study the ability of curcumin to protect against the ... Read more