Amal Khalifa Ahmed Noreldin

Professor - Assistant professor of Internal Medicine

Faculty of medicine

Address: سوهاج شارع النيل برج عزالدولة


Study of patients with nephrotic syndrome in Sohag University Hospital
Background Nephrotic syndrome is not a disease; it is the manifestation of a wide variety of underlying disease processes. Objectives The aim of the present study was to investigate different clinic-laboratory and histological patterns of nephrotic syndrome and the relationship between its clinical character and prognosis. Methods From January 2010 to December 2011 the authors of the present study retrospectively ... Read more

Correlation between Liver Function Tests and Polymerase Chain Reaction in Chronic Hepatitis C Patients
BACKGROUND: Hepatitis C virus infection is currently the most significant public health problem globally and particularly in Egypt. The outcomes of HCV infection range from asymptomatic chronic infection, with normal or nearly normal liver functions, to severe chronic hepatitis, evolving rapidly to cirrhosis and hepatocellular carcinoma. Our objective is to asses and evaluates the relationship between liver function tests, serum ... Read more

Serum leptin level and butyrylcholinesterase enzyme activity in essential hypertension
BACKGROUND: Leptin, an adipocytokine was found to be associated with essential hypertension in several studies and butyrylcholinesterase enzyme (BChE) is an enzyme that hydrolyzes acetylcholine in plasma. Recent studies link between BChE and cardiovascular risk factors. OBJECTIVES: The aim of the present investigation was to study the relationship between serum leptin level and BChE enzyme activity in essential hypertension patients ... Read more

Vitamin D Level and Fok-I Vitamin D Receptor Gene Polymorphism in Egyptian Patients with Type-1 Diabetes
Many cellular, preclinical and observational studies support a role of vitamin D in pathogenesis of type-1 diabetes mellitus (DM). The vitamin D receptor (VDR) locus has been studied in different populations for association with susceptibility to immune-mediated diseases, but with inconsistent findings in type-1 DM. This study aimed to investigate vitamin D status in patients with type-1 DM. We examined ... Read more

Occult Hepatitis B Infection in Patients with Chronic Hepatitis C
Occult hepatitis B virus infection (OBI) is characterized by the presence of HBV DNA in the liver tissue or in the serum of HBsAg negative individuals. Although OBI was detected frequently in patients with chronic hepatitis C, the clinical implication of this co-infection is still not fully clarified. The aim of the present study was to assess the prevalence and ... Read more

Serum Levels of Adiponectin and Ghrelin in Patients with Acute Myocardial Infarction
BACKGROUND: Inflammation is widely known to play a key role in the development and progression of cardiovascular diseases. It has been observed that adipokines play an increasingly large role in systemic and local inflammation. Therefore, adipose tissue may have a more important role than previously thought in the pathogenesis of several disease types. We study serum levels of adiponectin and ... Read more

Angiotensin II enhances the increase in monocyte chemoattractant protein-1 production induced by tumor necrosis factor-α from 3T3-L1 preadipocytes
Monocyte chemoattractant protein-1 (MCP-1) and angiotensin II (Ang II) in adipose tissue are thought to induce systemic insulin resistance in rodents; but the precise mechanism is not fully clarified. We examined the mechanism of Ang II-induced and/or tumor necrosis factor-a (TNF-a)-induced MCP-1 production from 3T3- L1 preadipocytes. The MCP-1 protein and MCP-1 mRNA expression in 3T3-L1 preadipocytes were increased significantly ... Read more

The Effect of Angiotensin Receptor Blockers or Thiazolidinediones on Inflammatory Cytokines in Diabetic State
Evidence has been accumulated that some of the angiotensin II type 1 receptor blockers have insulin- sensitizing property. Insulin resistance is the comer stone not only in the development of type 2 diabetes mellitus but also in the development of most of its vascular complications. Insulin resistance is associated with a chronic low grade inflammation. Proinflammatory cytokines are recently reported ... Read more