BACKGROUND: Unfortunately burns are a common problem, leading to scarring or death. Platelet rich plasma (PRP) is a well known method that could be used as topical application for burn either second or third degree; it harbors many growth factors that can accelerate the healing. This study aimed: to analyze the use of PRP in deep second-degree burn, in comparison ... Read more

INTRODUCTION: Peripheral neuropathy is a major side effect of chemotherapy. Nerve growth factor induces peripheral nerve regeneration. Retinoids play a significant role in neural growth. AIM OF THIS STUDY was to compare the curative effect of recombinant human nerve growth factor (Rh-NGF) and all trans-retinoic acid (ATRA) alone or together on taxol induced peripheral neuropathy. MATERIALS AND METHODS: Fifty two ... Read more

Purpose: The aim of this study was to detect the clinical and histological effects of preoperative subconjunctival injection of both bevacizumab and mitomycin C (MMC) 1 month before the surgical excision of primary pterygium using a bare sclera technique. Patients and methods: A total of 20 patients with primary pterygium underwent subconjunctival combined injection of 0.1 mL of MMC (0.1 ... Read more

Introduction: Cirrhosis is the end stage of any chronic liver disease. It is characterized by diffuse fibrosis with disturbed hepatic architecture. Omega-3 polyunsaturated fatty acids are common antioxidant, anti-inflammatory and anti-fibrotic agents Aim: This study was conducted to investigate the potential effects of omega-3 fatty acids on experimentally induced cirrhosis. Materials and Methods: 60 animals were divided into three groups: ... Read more

Introduction: Patulin is considered the most common mycotoxins in moldy fruits especially apples and its products like juice and compote. Goji berry (lycium barbarum fruit) is a traditional Chinese herb. It has several biological activities as antioxidant, anti-aging and hypoglycemic properties. Aim: To demonstrate the toxic effect of patulin on the pancreatic tissue and to evaluate the possible role of ... Read more

Introduction: Aspartame is the most widely used artificial sweeteners. Stevia is a worldwide natural sweetener plant with medicinal and commercial importance. Stress responses are mediated both in the central and peripheral nervous system. The principal effectors of the stress response are localized in the hypothalamus, the anterior lobe of the pituitary gland, and the adrenal gland. This is commonly referred ... Read more

Introduction: Monosodium glutamate is widely used either as preservatives or enhancer of palatability. It is toxic to both human and experimental animals. Ascorbic acid is a natural antioxidant and has broad spectrum pharmacological properties. Aim of the work:The aim of the study was to determine the effect of monosodium glutamate on the structure of the spleen and to detect the ... Read more

Introduction Titanium dioxide nanoparticles (TiO 2 NPs) are manufactured worldwide for various bioengineering applications. They are frequently used in medicine, in sun protection creams, and in industries such as paints. However, these nanoparticles can induce pulmonary toxicity and its mechanism and prevention is not fully understood. Objective This study aimed to investigate the effect of TiO 2 NPs on histological ... Read more

Paracetamol (acetaminophen) (PA) is a widely used as an analgesic and antipyretic drug that is commonly available in without a prescription. Paracetamol has been used to treat many diseases such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It cures pain in mild arthritis but has no effect on the underlying inflammation and swelling of the joints. It ... Read more

Many patients with corneal opacity or complicated cataract in blind eye ask for cosmoses. In this study we tried to investigate the staining of corneas of male rabbits by Rotring China painting ink and to study the histological changes. Method. 10 eyes of 10 male Baladi Egyptian rabbits were injected (0.1 mL) intrastromally in the cornea by the use of ... Read more