Hoda Mostafa Ahmed

استاذ مساعد - Head of Physiology departement

كلية الطب

العنوان: Sohag University - Faculty of Medicine - Physiology departement


2017 | الكلمات المفتاحية INTERFERON-γ, hepatitis C virus, Gene polymorphism,
Interlukin-10 and Interferon Gamma Gene Polymorphisms and Hepatitis C Virus-Related Liver Cirrhosis Risk
ABSTRACT: _OBJECTIVES:_ We aimed to find the relation between the gene polymorphisms in interleukin-10 and interferon- γ genes with susceptibility and severity of HCV infection among Egyptian patients. _PATIENTS AND METHODS_: Interleukin-10 -592 A/C, -1082 G/A and IFN-γ +874 T/A genotypes were determined in 50 chronic HCV patients, 50 HCV cirrhotic patients and 50 health controls. _RESULTS_: IL10-592A/C polymorphism genotyping ... إقراء المزيد

2016 | الكلمات المفتاحية rats, prepubertal, oset of puberty, leptin,
The Effect of Leptin on the Onset of Puberty in Normal Prebupertal Female Albino Rats
ABSTRACT BACKGROUND: Many studies have focused on leptin, the product of the LEP (ob) gene, searching for a possible link between energy balance and reproduction. OBJECTIVE: Investigating the effect of daily leptin injection on prepubertal female rats and the possible mechanisms by which leptin can affect reproductive axis. MATERIALS AND METHOD: This study was applied on eighty female albino rats ... إقراء المزيد

2016 | الكلمات المفتاحية Steroidogenesis., Streptozotocin-induced diabete, Growth factors, Selenium,
Selenium  increases Testicular Steroidogenesis and Growth factors Expression in Streptozotocin-induced Diabetic Rats
ABSTRACT Selenium (Se) is an essential trace element and found to have important roles in maintaining normal growth and reproduction. The effect of Se on testicular steroidogenesis and testicular expression of vascular endothelial growth factor (VEGF) and nerve growth factor-beta (NGF-β) was studied in streptozotocin (STZ)- induced diabetic rats. The study included 45 male albino rats randomly divided into 3 ... إقراء المزيد

2016 | الكلمات المفتاحية Sirtuin 1, Gene polymorphism, Essential hypertension, Type 2 diabetes mellitus,
Association of sirtuin 1 gene single nucleotide polymorphisms with type 2 diabetes mellitus in essential hypertension patients
ABSTRACT Sirtuin 1 (SIR1) is a NAD+-dependent nuclear deacetylase that is involved in various metabolic pathways affecting energy homeostasis. In this investigation,we aimed to study the association of three SIRT1 gene single nucleotide polymorphisms (SNPs); rs7895833 A/G, rs7069102 C/G and rs2273773 C/T, located on the promotor, intron and exon regions respectively, with essential hypertension and type 2 diabetes mellitus (T2DM). ... إقراء المزيد

Serum leptin level and butyrylcholinesterase enzyme activity in essential hypertension patients
ABSTRACT BACKGROUND: Leptin, an adipocytokine was found to be associated with essential hypertension in several studies and butyrylcholinesterase enzyme (BChE) is an enzyme that hydrolyzes acetylcholine in plasma. Recent studies link between BChE and cardiovascular risk factors. OBJECTIVES: The aim of the present investigation was to study the relationship between serum leptin level and BChE enzyme activity in essential hypertension ... إقراء المزيد

2013 | الكلمات المفتاحية angiogenesis, leptin,
Leptin and Angiogenesis
ABSTRACT Leptin is a 16 KDa protein, consists of 167 amino acid residues. It has many functions including angiogenesis. Leptin either induces angiogenesis itself or influences the levels of other angiogenic factors. The aim of the present investigation was to study the effect of leptin on the levels of the angiogenic factors: vascular endothelial growth factor (VEGF) and thymidine phosphorylase ... إقراء المزيد

2012 | الكلمات المفتاحية procalcitonin, C-reactive protein, diagnosis, neonatal sepsis,
Procalcitonin or C-reactive protein or both for diagnosis of neonatal sepsis?
ABSTRACT _BACKGROUND__: _Early recognition and diagnosis of neonatal sepsis is difficult because of the variable and non-specific clinical presentation of this condition. It is extremely important to make an early diagnosis of neonatal sepsis for the prompt institution of anti-microbial therapy, which improves outcomes. _AIMS: _The aim of this study was to determine the role of Procalcitonin (PCT) and C-reactive ... إقراء المزيد

2012 | الكلمات المفتاحية ACCP antibody, rheumatoid factor, diagnosis, Rheumatoid Arthritis,
Anti-cyclic citrullinated peptide (ACCP) antibody versus rheumatoid factor (RF) for diagnosis of rheumatoid artheritis
ABSTRACT INTRODUCTION: Rheumatoid arthritis (RA) is an inflammatory autoimmune disease characterized by chronic joint inflammation and extra-articular manifestations culminating in permanent disability without early therapeutic interventions. Early accurate diagnosis and therefore treatment of rheumatoid arthritis (RA) has become increasingly important. AIM OF THE WORK: To compare the diagnostic power of anti-cyclic citrullinated peptide (ACCP) antibody to rheumatoid factor (RF) in ... إقراء المزيد