ahmed_ahmed4

Ahmed Roshdi Hamed Ahmed

Professor - Professor of Pathology

Faculty of medicine

Address: Sohag, Naser City.

27

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2016 | Keywords HCV genotype 4, Steatosis, VAI, TyG, IR,
Insulin Resistance, Visceral Adiposity Index and TyG Index in Genotype-4 Chronic HCV Patients and Their Relation to Hepatic Histopathology
INTRODUCTION: Hepatitis C virus (HCV) genotype 4 is the most prevalent in Egypt. Vis-ceral adiposity index (VAI) and (TyG) index are newly developed indices for assess-ment of metabolic syndrome (MS) and insulin resistance (IR). We aimed at comparing their levels in HCV-patients with healthy controls and validate their use for prediction of hepatic histopathological changes. PATIENT AND METHODS: 78 chronic ... Read more

Ocular Surface Disorders in a Group of Egyptian Children with End Stage Renal Failure on Dialysis: A Cross-Sectional Study
Purpose . To investigate tear function, ocular manifestations, and squamous metaplasia of the conjunctival epithelium (SMCE) in children with end stage renal failure (ESRF) on dialysis. Methods . Thirty children with ESRF and 20 age and sex matched controls during the period from January 2014 to May 2015 underwent full ophthalmologic examination and the tear function was investigated by the ... Read more

2016 | Keywords H . Pylori, chronic gastritis, P53,
Immunohistochemical Detection of P53 in Helicobacter Pylori Gastritis
Abstract: Aim of the work: This study was designed to detect mutation in P53 in cases of non-neoplastic Helicobacter Pylori (H. Pylori) gastritis. Method: 55 cases of chronic H. Pylori gastritis were selected and we used immunohistochemical technique to detect P53 expression and compared it with the five parameters in Sydney system (gastric atrophy, intestinal metaplasia, chronicity, and activity and ... Read more

2016 | Keywords
Pathogenesis and Bone Resorption in Acquired Cholesteatoma: Current Knowledge and Future Prospectives
Cholesteatoma is a cystic non tumorous lesion of the temporal bone that has the ability to destroy nearby structures by its power to cause bone resorption and as a result, fatal complications prevail. We aimed to conduct a comprehensive review for pathogenesis of acquired cholesteatoma, bone resorption mechanisms, and offer a future vision of this serious disease. We have reviewed ... Read more

HER2 expression is a strong independent predictor of nodal metastasis in breast cancer
Identification of metastatic potential of breast cancer cells is necessary for proper management of this disease. This work aimed to estimate likelihood of axillary lymph node (ALN) involvement in breast cancer patients based on human epidermal growth factor receptor 2 (HER2) expression. Primary tumors of 317 breast cancer patients were evaluated for estrogen receptor (ER), progesterone receptor (PR) and HER2 ... Read more

Expression of β-Catenin in Locally Aggressive Mammary Ductal Carcinoma
Background and Aim: β-catenin is a cell membrane mol-ecule that is essential for cell-cell adhesion of normal epithelia. It is down-regulated in several epithelial tumors and its expression is correlated with tumor cell invasion and metasta-sis. The aim of this study was to evaluate expression status and angiogenic effect of β-catenin in locally aggressive mammary carcinoma. Methods: Formalin-fixed paraffin embedded ... Read more

NECROTIZING FASCIITIS; DIAGNOSTIC PARAMETERS FOR EARLY DETECTION AND SUBSEQUENT IMPROVED SURGICAL OUTCOME
ARTICLE INFO ABSTRACT Aim of the work timing of presentation and surgical interference. Patients and methods University Hospital from July 2010 to April 2014. Necrotizing fasciitis (NF) was diagnosed clinically and confirmed by intraoperative findings and routine postoperative histopathological criteria in association to laboratory values e.g. total leucocytic count; band leucocytes percentage and serum Na were recorded. According to these ... Read more

2015 | Keywords Esophagus Fistula Surgery,
Case report: Acquired esophago‑pulmonary fistula
Acquired esophago-respiratory fistulae are usually esophago-tracheal or esophago-bronchial. Esophagopulmonary fistulae have been rarely described. We report a case of 17-year-old girl with esophago-pulmonary fistula. She experienced a long history of cough and expectoration. CT scans of the chest demonstrated right lower and middle lung lobes multiple cavitary lesions with marked dilatation of the esophagus and a communicating fistula between the ... Read more

Rhinoscleroma: A detailed histopathological diagnostic insight
Rhinoscleroma (RS) is a chronic specific disease of nose and upper respiratory passages caused by Klebsiella rhinoscleromatis bacilli. It is endemic in Egypt and in sporadic areas worldwide. Diagnosis of RS depends on identification of the pathognomonic Mickulicz cells (MCs) which is most prominent during granulomatous phase but spares or absent during catarrhal or sclerotic phases of the disease. This ... Read more

2015 | Keywords EphB6 Prostate cancer,
Reduced expression of erythropoietin-producing hepatocyte B6 receptor tyrosine kinase in prostate cancer
Loss of erythropoietin-producing hepatocyte (Eph) B6 gene expression is associated with poor prognosis in neuroblastoma, melanoma and other tumors. The present study evaluated the expression of EphB6 receptor tyrosine kinase in normal and prostate cancer tissue using immuno-histochemistry. The association between EphB6 expression, clinicopathological findings, proliferating-cell nuclear antigen (PCNA; another prognostic marker) and progression of prostate cancer was analyzed. Tissue ... Read more