An Efficient One Pot Three-Components Synthesis of Some New Polyhydroquinolines via Enaminone Intermediates;
For a wide spectrum of pharmacological effects of polyhydroquinolines, this study introduces a developed safe, simple, higher yields and fast method for the synthesis of some new hexahydroquinoline derivatives using one-pot three-component cyclocondensation reaction, via the reaction of 1,3-cyclohexanedione with primary amine and arylidinemalononitrile or salicylaldehyde derivatives. The prepared compounds were reacted with different reagents as N,N-dimethylformamide dimethylacetal, acetic anhydride, ... Read more