Markers defining colorectal adenoma-carcinoma progression: a computerized image analysis protocol
ABSTRACT: The vast majority of colorectal carcinoma are widely believed to arise from polypoid adenomas. The apoptotic related genes that have been most consistently characterized in colonic cancer are bcl-2, bax, and p53. Studying the expression of these genes in adenoma carcinoma sequence will be of great value in producing the clinical behavior of benign tumors. Loss of contact inhibition ... Read more