Serum Soluble Fas, Bcl-2 Proteins and IL-6 Levels in Patients with Psoriasis Vulgaris and their correlations to disease activity.
INTRODUCTIONF: as (Apo-I /CD95) is a widely expressed membrane-anchored protein that induces apoptosis. Keratinocytes constitutively express the Fas antigen and Fas- mediated apoptosis may characterize several pathological conditions affecting human skin. Soluble Fas (sFas) has been demonstrated in serum by alternative mRNA splicing of Fas receptor. It can antagonize cell surface Fas function by downregulating Fas- mediated apoptosis and its ... Read more