Role of Serum Matrix Metalloproteinase-1 and Tumor Necrosis Factor- α in Rheumatoid Arthritis and Osteoarthritis
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by joint inflammation and destruction resulting in degradation of extracellular cartilage matrix. Osteoarthritis (OA) is also associated with degradation of molecular components of cartilage matrix with eventual loss of joint cartilage function. Matrix metalloproteinases (MMPs) are a family of proteinases modulated enzymes that play an important role in the pathogenesis ... إقراء المزيد