ahmedabudief

Dr. Ahmed Mohammed Abu-Dief Mohammed

Assistant Professor - Assistant professor of Inorganic and Physical Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street

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Publications Which contain the keyword: 1


Green synthesis of TiO2 nanoparticles as an efficient heterogeneous catalyst with high reusability for synthesis of 1,2-dihydroquinoline derivatives
Nano materials find wide applications due to their behavior at nano scale. TiO2 nanoparticles (TiO2 NPs) was synthesized using Neem leaf extract. This is simple, rapid, eco-friendly, cheaper and green tools for TiO2 NPs synthesis using agricultural waste at lower applied temperature. Characterization of the extracted TiO2 NPs was confirmed by XRD, SEM, EDAX, TEM, HR-TEM, SAED, and FT-IR, respectively. ... Read more

Novel aryl carboximidamide and 3-aryl-1,2,4-oxadiazole analogues of naproxen as dual selective COX-2/15-LOX inhibitors: Design, synthesis and docking studies
A series of novel naproxen analogues containing 3-aryl-1,2,4-oxadiazoles moiety (4B-G) and their reaction intermediates aryl carboximidamides moiety (3B-G) was synthesized and evaluated _in vitro_ as dual COXs/15-LOX inhibitors. Compounds 3B-G exhibited superior inhibitory activity than celecoxib as COX-2 inhibitors. Compounds 3B-D and 3G were the most potent COX-2 inhibitors with IC50 range of 6.4 – 8.13 nM and higher selectivity ... Read more

2018-11-14 13:47:52 Keywords 1, 2, 4-Triazole,
Synthesis and Antibacterial Activity of Some New 4-anilino-5-phenyl-4H-1,2,4-triazole-3-thiol derivatives
4-Anilino-5-phenyl-4H-1,2,4-triazole-3-thiol (1) reacted with formaldehyde and different amines to give Mannich bases 2a–i. Treatment of compound 1 with formaldehyde afforded the corresponding 2-hydroxymethyl derivative 3, which upon its reaction with thionyl chloride yielded the corresponding chloromethyl derivative 4. Treatment of compound 4 with some thiols gave the corresponding sulfides 5a–f. The ring closure reaction of chloromethyl derivative 4 with hydrazine ... Read more

2018-10-30 09:47:43 Keywords Substituted(1, 5)benzodiazepin, 1, 3-Oxazino, 1, 3-Oxazine, 1, 2, 4-Triazole,
A Novel Synthesis of Pyrano(2,3-c)-1,3-Oxazino(2,3-b)-1,2,4-Triazolo(3,4-b)- and 3-Substituted(1,5)benzodiazepin-2-one
A Novel Synthesis of Pyrano(2,3-c)-1,3-Oxazino(2,3-b)-1,2,4-Triazolo(3,4-b)- and 3-Substituted(1,5)benzodiazepin-2-one Read more

2018-10-30 09:47:43 Keywords Substituted(1, 5)benzodiazepin, 1, 3-Oxazino, 1, 3-Oxazine, 1, 2, 4-Triazole,
A Novel Synthesis of Pyrano(2,3-c)-1,3-Oxazino(2,3-b)-1,2,4-Triazolo(3,4-b)- and 3-Substituted(1,5)benzodiazepin-2-one
A Novel Synthesis of Pyrano(2,3-c)-1,3-Oxazino(2,3-b)-1,2,4-Triazolo(3,4-b)- and 3-Substituted(1,5)benzodiazepin-2-one Read more

2018-10-30 09:47:43 Keywords Substituted(1, 5)benzodiazepin, 1, 3-Oxazino, 1, 3-Oxazine, 1, 2, 4-Triazole,
A Novel Synthesis of Pyrano(2,3-c)-1,3-Oxazino(2,3-b)-1,2,4-Triazolo(3,4-b)- and 3-Substituted(1,5)benzodiazepin-2-one
A Novel Synthesis of Pyrano(2,3-c)-1,3-Oxazino(2,3-b)-1,2,4-Triazolo(3,4-b)- and 3-Substituted(1,5)benzodiazepin-2-one Read more

2018-10-30 09:31:59 Keywords Spiro 1, 3-Dithiin, 1, 3-Thiazine, Cyanoketene acetals, PTC conditions,
A Novel Synthesis of Spiro 1,3-Dithiin and 1,3-Thiazine Derivatives Via Cyanoketene acetals under PTC conditions.
A Novel Synthesis of Spiro 1,3-Dithiin and 1,3-Thiazine Derivatives Via Cyanoketene acetals under PTC conditions. Read more

2018-10-30 09:30:23 Keywords 1, 4-Diazepines, Thieno(2, 3-b)thiophene, Cyclohexene Carboxylate,
1,4-Diazepines Bearing Thieno(2,3-b)thiophene and Cyclohexene Carboxylate Moieties"
1,4-Diazepines Bearing Thieno(2,3-b)thiophene and Cyclohexene Carboxylate Moieties" Read more

2018-10-18 19:58:49 Keywords 1, 5 Benzodiazepines,
Hetaryl-1,5 benzodiazepines Part I: Synthesis of 3-pyrimidyl- and imidazolyl-1,5-benzodiazepines
Nucleophilic substitution of 3-bromo-4-phenyl-1H-[1,5]benzodiazepin-2-one (1) with thiourea or guanidine in presence of potassium carbonate afforded 1,5-benzodiazepin-3-ylimidothiocarbamate 2 or 1,5- benzodiazepin-3-ylguanidine 3, respectively. Pyrimidylthiobenzodiazepines 5–13 were obtained via the reaction of compound 2 with malononitrile dimer, diethyl malonate, methylenemalononitriles, or a mixture of an aldehyde and β-keto esters or acetylacetone, catalyzed using ceric ammonium nitrate. Reaction of compound 2 or 3 ... Read more

An Efficient One Pot Three-Components Synthesis of Some New Polyhydroquinolines via Enaminone Intermediates;
For a wide spectrum of pharmacological effects of polyhydroquinolines, this study introduces a developed safe, simple, higher yields and fast method for the synthesis of some new hexahydroquinoline derivatives using one-pot three-component cyclocondensation reaction, via the reaction of 1,3-cyclohexanedione with primary amine and arylidinemalononitrile or salicylaldehyde derivatives. The prepared compounds were reacted with different reagents as N,N-dimethylformamide dimethylacetal, acetic anhydride, ... Read more