ahmedabudief

Dr. Ahmed Mohammed Abu-Dief Mohammed

Assistant Professor - Assistant professor of Inorganic and Physical Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street

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Publications Which contain the keyword: 2


β-RA reduces DMQ/CoQ ratio and recues the encephalopathic phenotype in Coq9R239X mice
Coenzyme Q (CoQ) deficiency has been associated with primary defects in the CoQ biosynthetic pathway or to secondary events. In some cases, the exogenous CoQ supplementation has limited efficacy. In the Coq9R239X mouse model with fatal mitochondrial encephalopathy due to CoQ deficiency, we have tested the therapeutic potential of b-resorcylic acid (b-RA), a structural analog of the CoQ precursor 4-hydroxybenzoic ... Read more

Differential tolerance to high salt with regard to cell growth and superoxide dismutase (SOD) activity in calluses of the halophyte Suaeda maritima from Japan and Egypt
To determine the mechanism of regulation of superoxide dismutase (SOD; EC 1.15.1.1) isozymes in halophytes at the cellular level,we isolated calluses from Suaeda maritima plants native to Japan and Egypt. Calluses from Egyptian S. maritima could grow in a high salt medium (~400 mM NaCl), whereas Japanese S. maritima calluses could not. The expression characteristics of SOD isozyme genes encoding ... Read more

2018-11-14 13:47:52 Keywords 1, 2, 4-Triazole,
Synthesis and Antibacterial Activity of Some New 4-anilino-5-phenyl-4H-1,2,4-triazole-3-thiol derivatives
4-Anilino-5-phenyl-4H-1,2,4-triazole-3-thiol (1) reacted with formaldehyde and different amines to give Mannich bases 2a–i. Treatment of compound 1 with formaldehyde afforded the corresponding 2-hydroxymethyl derivative 3, which upon its reaction with thionyl chloride yielded the corresponding chloromethyl derivative 4. Treatment of compound 4 with some thiols gave the corresponding sulfides 5a–f. The ring closure reaction of chloromethyl derivative 4 with hydrazine ... Read more

2018-10-30 09:47:43 Keywords Substituted(1, 5)benzodiazepin, 1, 3-Oxazino, 1, 3-Oxazine, 1, 2, 4-Triazole,
A Novel Synthesis of Pyrano(2,3-c)-1,3-Oxazino(2,3-b)-1,2,4-Triazolo(3,4-b)- and 3-Substituted(1,5)benzodiazepin-2-one
A Novel Synthesis of Pyrano(2,3-c)-1,3-Oxazino(2,3-b)-1,2,4-Triazolo(3,4-b)- and 3-Substituted(1,5)benzodiazepin-2-one Read more

Ketene N,S-acetals in heterocyclic synthesis: Part 1: Synthesisof N-phenyl-2-ylidene and 2,5-diylidene-4-thiazolidinone derivatives"
Ketene N,S-acetals in heterocyclic synthesis: Part 1: Synthesisof N-phenyl-2-ylidene and 2,5-diylidene-4-thiazolidinone derivatives" Read more

Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network
Multiple studies reporting mitochondrial impairment in Parkinson’s disease (PD) involve knockout or knockdown models to inhibit the expression of mitochondrial-related genes, including parkin, PINK1, and DJ-1 ones. Melatonin has significant neuroprotective properties, which have been related to its ability to boost mitochondrial bioenergetics. The meaning and molecular targets of melatonin in PD are yet unclear. Zebrafish are an outstanding model ... Read more

2018-09-24 11:03:45 Keywords 4]triazole, 2, pyrazolyl-[1,
Synthesis of 3-Pyrazolyl-1,2,4-Triazoles via One-Pot Multicomponent Reaction in Phosphoric Acid
A high-yielding synthetic route towards pyrazolyl-[1,2,4]triazole derivatives has been developed via one-pot multicomponent reaction of polyfunctionalized triazoles, DMF-DMA, acetophenone, ethyl cyanoacetate, and/or 3-oxo-3-phenylpropanenitrile in _ortho_-phosphoric acid (85%). In the same manner, a new series of 2-triazolyl-tetrahydro-indazol-4-ones and pyrazolo[3,4-_d_]pyrimidines has been synthesized by reaction of triazoles, DMF-DMA and 1,3-cyclohexanediones and/or barbituric acid, respectively. The same products were prepared a classical manner ... Read more

Synthesis of 2-(2-methyltetrazol-5-yl)-2,2-dinitroacetonitrile. Reaction of the nitrile group with diazomethane
The reaction of the silver salt of (2-methyltetrazol-5-yl)dinitromethane with cyanogen bromide led to the formation of 2-(2-methyltetrazol-5-yl)-2,2-dinitroacetonitrile. The nitrile group of the latter was capable of entering into 1,3-dipolar cycloaddition with diazomethane, giving a mixture of isomeric 2-methyl-5-[(_N_-methyl-1,2,3-triazol-4-yl)dinitromethyl]tetrazoles that were separated by column chromatography. Upon treatment with an alcohol solution of potassium hydroxide, denitration of the cycloaddition products occurred and ... Read more

2018-09-14 16:26:18 Keywords Pyrazoles-triazo;es, 4]triazole - 2-, 2, pyrazolyl-[1,
Synthesis of 3-pyrazolyl-1,2,4-triazoles via one-pot multicomponent reaction in phosphoric acid
A high-yielding synthetic route towards pyrazolyl-[1,2,4]triazole derivatives has been developed via one-pot multicomponent reaction of polyfunctionalized triazoles, DMF–DMA, acetophenone, ethyl cyanoacetate, and/or 3-oxo-3-phenylpropanenitrile in ortho-phosphoric acid (85%). In the same manner, a new series of 2-triazolyl-tetrahydro-indazol-4-ones and pyrazolo[3,4-d]pyrimidines has been synthesized by reaction of triazoles, DMF–DMA and 1,3-cyclohexanediones and/or barbituric acid, respectively. The same products were prepared a classical manner ... Read more

2018-09-03 16:50:52 Keywords وقد استخدام البحث المنهج شبه التجريبي ذ, وتم بعد ذلك تطبيق اختبار تصويب التصورات, إعادة صياغة موضوعات وحدة, . 3, جغرافية الإنسان والبيئة والتنمية, قائمة بالقضايا البيئية المعاصرة المتضمن, والتي لدي طلاب الصف الأول الثانوي تصورا, قائمة بالمفاهيم الجغرافية المتضمنة في و, ما أثر استخدام استراتيجية التعارض المعر, 2, المقررة علي طلاب الصف الأول الثانوي, الأخطار التي تهدد البيئة, ما التصورات البديلة للمفاهيم الجغرافية, 1, استهدفت هذه الدراسة : التعرف علي أثر اس, أستاذ مساعد المناهج وطرق تدريس ال, العنوان: أثر استخدام استراتيجية التعارض, التصورات البديلة للمفاهيم, تصويب Correct, المفاهيم الجغرافية (Geographical Concep, استراتيجية التعارض المعرفي (Strategy Co, خالد عبد ا, أكتوبر 2013م .إعداد: د, طلاب المرحلة الثانوية, الوعي ببعض القضايا البيئية المعاصرة, تصويب التصورات البديلة للمفاهيم الجغراف, تدريس الجغرافيا, استراتيجية التعارض المعرفي, أثر استخدام, بحوث تربوية متنوعة, خالد عبد اللطيف محمد عمران, أ.د, أثر استخدام استراتيجية التعارض المعرفي, 105). تاريخ النشر : أكتوبر 2013م, الصفحات (65, الجزء الثالث, ع (42), النفس,
أثر استخدام استراتيجية التعارض المعرفي في تدريس الجغرافيا علي تصويب التصورات البديلة للمفاهيم الجغرافية وتنمية الوعي ببعض القضايا البيئية المعاصرة لدي طلاب المرحلة الثانوية
مستخلص البحث العنوان: أثر استخدام استراتيجية التعارض المعرفي في تدريس الجغرافيا علي تصويب التصورات البديلة للمفاهيم الجغرافية وتنمية الوعي ببعض القضايا البيئية المعاصرة لدي طلاب المرحلة الثانوية. إعداد: د/خالد عبد اللطيف محمد عمران– أستاذ مساعد المناهج وطرق تدريس الدراسات الاجتماعية – كلية التربية – جامعة سوهاج . جهة النشر:مجلة دراسات عربية في التربية وعلم النفس، ع (42) ، الجزء الثالث، ... Read more