amr_hassanegypt

Amr Hassan Moustafa Ahmed

Assistant Professor - Assistant Professor

Faculty of science

Address: Al-Iman Tower, Al-Sharaieh Street, behind the university's dormitory for girls' students, Nasser City - Sohag

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Publications Which contain the keyword: Naproxen


3.	Novel aryl carboximidamide and 3-aryl-1,2,4-oxadiazole analogues of naproxen as dual selective COX-2/15-LOX inhibitors: Design, synthesis and docking studies
A series of novel naproxen analogues containing 3-aryl-1,2,4-oxadiazoles moiety (4b-g) and their reaction intermediates aryl carboximidamides moiety (3b-g) was synthesized and evaluated in vitro as dual COXs/15-LOX inhibitors. Compounds 3b-g exhibited superior inhibitory activity than celecoxib as COX-2 inhibitors. Compounds 3b-d and 3g were the most potent COX-2 inhibitors with IC50 range of 6.4 – 8.13 nM and higher selectivity ... Read more

2018-10-29 12:52:55 Keywords Potential Chemotherapeutic Age, Naproxen,
Synthesis of New Potential Chemotherapeutic Agents Incorporating Naproxen Sub-Structure
Synthesis of New Potential Chemotherapeutic Agents Incorporating Naproxen Sub-Structure Read more

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