ahmedabudief

Dr. Ahmed Mohamed Abu-Dief

Professor - Professor of Physical and Inorganic Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street

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Publications Which contain the keyword: Antimicrobial activity


Design, Physicochemical Studies and DNA Interaction of Some Complexes
In recent years, great interest has been focused on Fe(II) Schiff bases amino acids complexes as cytotoxic and antitumor drugs. Thus a series of new iron(II) complexes based on Schiff bases amino acids ligands have been designed and synthesized from condensation of 2-hydroxy-1-naphthaldehyde and 5-bromosalicylaldehyde (bs) with α-amino acids ((L-alanine (ala), L-phenylalanine (phala), L-aspartic acid (aspa), L-histidine (his) and L-arginine ... Read more

Synthesis, theoretical investigations, biocidal screening, DNA binding, in vitro cytotoxicity and molecular docking of novel Cu (II), Pd (II) and Ag (I) complexes
Three new Cu(II), Pd(II) and Ag(I) complexes with bi-dentate Schiff base ligand "HL" namely 2-[(4-Chloro-benzylidene)-amino]-phenol were synthesized. The stoichiometric ratios and physicochemical properties of these complexes were determined using elemental analyses (C, H, and N), magnetic measurements, IR, UV-Vis spectra, molar conductivity and thermal analyses. The results revealed that the metal ions coordinated with ligand HL through azomethine nitrogen and ... Read more

Physicochemichal properties, DNA interaction, antiviral and antioxidant activities of some Amino Acid Imine Chelates
Schiff base amino acid ligands which derived from the condensation of 3-methoxysalicylaldehyde (MS) or 4-diethylaminosalicylaldehyde (DS) with some of α-amino acids (Phenylalanine (Phe), Histidine (His), Tryptophan (Trp)) were prepared. Moreover, eleven Schiff base amino acid binary Fe(II) and Cu(II) complexes were prepared. In addition to, five ternary Cu(II) complexes which derived from the prepared Schiff base amino acid ligands as ... Read more

Ni(II) and Cu(II) complexes : synthesis, spectroscopic characterization, theoretical calculations, DNA interaction and antimicrobial studies
A novel Schiff base, namely _Z_‐3‐((2‐((_E_)‐(2‐hydroxynaphthyl)methylene)amino)‐5‐nitrophenylimino)‐1,3‐dihydroindin‐2‐one, was synthesized from the condensation of 2‐hydroxy‐1‐naphthaldehyde and isatin with 4‐nitro‐_o_‐phenylenediamine. It was structurally characterized on the basis of 1H NMR, 13C NMR and infrared spectra and elemental analyses. In addition, Ni(II) and Cu(II) complexes of the Schiff base ligand were prepared. The nature of bonding and the stereochemistry of the investigated complexes were ... Read more

Synthesis, Characterization, Antimicrobial evaluation and DFT calculations of Fe(III), Ni(II) and Cu(II) complexes of tridentate ONO donor ligand
A series of Fe(III), Ni(II) and Cu(II) complexes of the type [Fe(L)(H2O)2Cl].2H2O, [Ni(L)(H2O)].2H2O and [Cu(L)(H2O)3].2H2O, where L bi-negatively tridentate Schiff base ligand derived from condensation between anthranilic acid and 2-hydroxy-benzaldhyde, have been synthesized. The proposed structures of the obtained complexes have been established from elemental analyses, UV-Vis., FT-IR, magnetic moment and conductivity measurements. Density Functional Theory (DFT) calculations were established ... Read more