ahmedabudief

Dr. Ahmed Mohammed Abu-Dief Mohammed

Assistant Professor - Assistant professor of Inorganic and Physical Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street

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Publications Which contain the keyword: anticancer activity


Novel Azomethine Pd(II) and VO(II)  Based Metallo-Pharmaceuticals as Anticancer, Antimicrobial and Antioxidant  agents:  Design, Structural inspection,  DFT investigation and DNA interaction
The new NO bi-dentate imine ligand namely (2-[(3-Nitro-benzylidene)-amino]-benzoic acid) (NBA) imine ligand (L) and their Pd(II) and VO(II) complexes have synthesized and characterized utilizing different physiochemical methods including elemental analyses, FT-IR, NMR, molar conductance and magnetic susceptibility measurements. The stability constant of these complexes has also determined. The studies of these complexes were found to have [M (L)] composition where ... Read more

Antimicrobial and anticancer activities of cobalt (III)-hydrazone complexes: Solubilities and chemical potentials of transfer in different organic co-solvent-water mixtures
The present study focused on the measurement of the solubilities and the calculation of the chemical potentials of transfer of Co(III)-hydrazone complexes in mixtures of water and ethyl alcohol (EtOH), isopropyl alcohol (_i_-PrOH), or _tert_-butyl alcohol (_t_-BuOH) at 298 K, using the assumption that dm mq Ph4As+ = dm mq BPh4- (TATB). A comparison between the chemical potentials of transfer ... Read more

Fabrication, Spectroscopic Characterization, Calf thymus DNA Binding Investigation, Antioxidant and Anti-cancer Activities of Some Antibiotic Azomethine Cu(II), Pd(II), Zn(II) and Cr(III) Complexes
This study was conducted to prepare novel azomethine chelates of Cu(II), Pd(II), Zn(II) and Cr(III) with tri-dentate dianionic azomethine OVAP ligand 2-[(2-Hydroxy-phenylimino)-methyl]-6-methoxy-phenol. The prepared compounds were characterized with the help of elemental analyses, spectral (NMR, FT-IR, UV-vis, mass), conductivity, magnetic and thermal measurements. The spectroscopic data suggest that the parent azomethine ligand bind to the investigated metal ions through both ... Read more

New palladium (II) and silver (I) Schiff base complexes Promising antibiotic and anticancer agents
Some new complexes derived from Ag (I) and Pd(II) metal ions and HNA imine ligand (L) _i.e. _(2-[(6-Allylidene-2-hydroxy-cyclohexa-1,3-dienylmethylene)-amino]-benzoic acid) have been synthesized and characterized by elemental analyses, molar conductance, magnetic susceptibility measurements, IR, NMR and electronic spectral studies. Moreover, the stability constants of the synthesized complexes were determined spectrophotometrically. On the basis of molar conductance and elemental analyses the complexes ... Read more

Three novel Ni(II), VO(II) and Cr(III) mononuclear complexes: Synthesis, structural characterization, DNA interaction, antimicrobial evaluation and anticancer activity
Three novel Cr(III),VO(II) and Ni(II) imine complexes derived from the condensation of 2‐aminophenol (AP) with 2‐hydroxynaphthaldehyde (HN) were synthesized. The prepared HNAP imine ligand and its complexes were investigated via various physicochemical tools. The results suggest that the parent ligand behaves as a dibasic tridentate ONO ligand, when coordinated to Cr(III) in octahedral and to Ni(II) in tetrahedral geometry. In ... Read more