Oral Hypoglycemic as Attractive Alternative to Insulin for the Management of Diabetes Mellitus during Pregnancy
OBJECTIVE: To study the efficacy and safety of glibenclamide/metformin combination as a treatment option for pregnant women with either gestational diabetes or type-2 diabetes mellitus compared to conventional insulin therapy. METHODS: Eighty-four pregnant women with singleton pregnancies (65 women with gestational diabetes & 19 with type-2 diabetes mellitus) were included. They were randomly allocated to receive either glibenclamide/metformin combination or ... Read more