Prophylactic and Ameliorative Effect of 𝑁-Acetylcysteine on Doxorubicin-Induced Neurotoxicity in Wister Rats
Doxorubicin (DOX) is an anthracycline antibiotic and a quinone-containing chemotherapeutic drug used for various types of cancers. However, as with most anticancer drugs, it causes many toxic effects, one of them is cognitive impairment. The present study investigated the prophylactic and ameliorative effect of n-acetylcysteine (NAC) against DOXinduced neurotoxicity in rats. Rats were divided into four groups. Control group: rats ... إقراء المزيد