eman_shalabi

Eman Muhammad Salah El-Deen Muhammad Shalabi

Professor - Professor of Pathology

Faculty of medicine

Address: القوصية - محافظة أسيوط

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Publications Which contain the keyword: HCV


2019-09-13 00:07:21 Keywords HCC, Epidemiology, HCV, Egypt, Globocan 2018,
Epidemiology and Risk Factors of Hepatocellular Carcinoma in Egypt
Hepatocellular carcinoma (HCC) is the most prevalent primary cancer of the liver accounting for 75% to 85% of primary liver cancers worldwide. It is the sixth most prevalent cancer in the globe and the fourth most prevalent cause of death from cancer, it occurs in males 2 to 3 times higher than in females. Geographical distribution of HCC varies throughout ... Read more

2019-02-18 12:47:15 Keywords VITAMIN D, HCC, HCV, Liver disease,
Vitamin D and Hepatitis C Virus-related Liver Disease
ABSTRACT Vitamin D through the vitamin D receptor (VDR) is involved in the control of bone and calcium homeostasis, immunoregulation, cellular differentiation, and anti-inflammatory actions. The liver is central in vitamin D synthesis, however the direct involvement of the vitamin D with chronic liver disease, chronic hepatitis C (CHC) infection, and hepatocellular carcinoma (HCC) remains to be evaluated. The purpose ... Read more

2018-10-25 09:08:34 Keywords Genotype 4, Steatosis, VAI, TyG, IR, HCV,
Insulin Resistance, Visceral Adiposity Index and TyG Index in Genotype-4 Chronic HCV Patients and Their Relation to Hepatic Histopathology
Introduction: Hepatitis C virus (HCV) genotype 4 is the most prevalent in Egypt. Visceral adiposity index (VAI) and (TyG) index are newly developed indices for assessment of metabolic syndrome (MS) and insulin resistance (IR). We aimed at comparing their levels in HCV-patients with healthy controls and validate their use for prediction of hepatic histopathological changes. Patient and Methods: 78 chronic ... Read more

2018-10-26 08:43:12 Keywords HCV, HBC, human immunodeficincy virus, thalassemia major,
Seroprevalence of Hepatitis C, Hepatitis B, Cytomegalovirus, and Human Immunodeficiency Viruses in Multitransfused Thalassemic Children in Upper Egypt
Background. Frequent blood transfusions in thalassemia major children expose them to the risk of transfusion-transmitted infections (TTIs). The aim of this study was to estimate the prevalence of hepatitis C virus (HCV), hepatitis B virus (HBV), human immunodeficiency virus (HIV), and cytomegalovirus (CMV) in thalassemic children attending the PediatricsDepartments of both Sohag andMiniaUniversities ofUpper Egypt, during the period fromMay 2014 ... Read more

2018-10-22 18:28:19 Keywords HCV, VEGF,
Vascular endothelial growth factor and hepatic neoangiogenesis in hepatitis C associated chronic liver disease
BACKGROUND Worldwide Egypt had the highest prevalence of hepatitis C virus infection. Angiogenesis is a complex process that regulated by many factors, including vascular endothelial growth factor (VEGF).in the liver HSCs, Kupffer cells, regenerating hepatocytes and existing endothelial cells are responsible for the process of neo angiogenesis and production of vascular endothelial growth factor (VEGF). AIM OF THE WORK: To ... Read more

2018-10-22 09:31:28 Keywords HCV, , CD34, ,
CD34 Expression as a marker of progression of chronic hepatitis C
BACKGROUND In Egypt, the rate of death/transplantation, decompensation and HCC in patients with compensated HCV cirrhosis is 4.58%, 6.37% and 3.36%, respectively. It is estimated that Egyptian patients with HCV cirrhosis had an annual incidence of HCC with 5.3%. CD34 is a 110-kDa transmembrane glycoprotein present on leukemic cells, endothelial cells and stem cells). CD34 is preferentially expressed on the ... Read more

2018-10-18 22:15:51 Keywords Bee venom, Therapy, traditional, HCV,
Efficacy of Bee Venom as an Anti-Viral Therapy for HCV Genotype 4
Abstract- Use of traditional medicine is encouraged in many economically diverse countries when conventional medications fail. HCV prevalence is highest in Egypt at >10% of the general population, and China has the most people with HCV (29.8 million); approximately 52% of patients infected with HCV genotype 4 will develop chronic HCV. The use of interferon, currently the only approved therapy, ... Read more

2018-09-15 12:49:15 Keywords Egypt, HCV,
Genetic Variability of Hepatitis C Virus in South Egypt and Its Possible Clinical Implication
Egypt is one of the countries with very high rates of hepatitis C virus (HCV) related morbidity and mortality. However, little is known about geographical and clinical differences in genetic variability of HCV in Egypt. Using direct sequencing and phylogenetic analysis of partial core/E1 and NS5B regions of the HCV genome, HCV genotype/subtype was determined in 129 HCVinfected patients residing ... Read more

2018-10-03 20:21:46 Keywords NK cells, HBV, HCV, Viral hepatitis,
Study some of natural killer cell phenotypes in viral hepatitis
ABSTRACT BACKGROUND& STUDY AIM: Natural killer (NK) cells are an integral part of the innate immune system. They have been suggestedto play an important role in both defense against viral hepatitis and the pathogenesis of other liver diseases. Our study aimsto investigating the expression of natural killer cells in viral hepatitis patients and if there is difference in those patients ... Read more

2018-10-02 13:30:04 Keywords HCV, IR, TyG, VAI, Steatosis, ,
Insulin Resistance, Visceral Adiposity Index and TyG Index in Genotype-4 Chronic HCV Patients and Their Relation to Hepatic Histopathology
Introduction: Hepatitis C virus (HCV) genotype 4 is the most prevalent in Egypt. Visceral adiposity index (VAI) and (TyG) index are newly developed indices for assessment of metabolic syndrome (MS) and insulin resistance (IR). We aimed at comparing their levels in HCV-patients with healthy controls and validate their use for prediction of hepatic histopathological changes. Patient and Methods: 78 chronic ... Read more