Semiquantitative Smoothelin Expression in Detection of Muscle Invasion in Transurethral Resection and Cystectomy Specimens in Cases of Urinary Bladder Carcinoma
ABSTRACT OBJECTIVES: To examine the usefulness of smoothelin - a new immunohistochemical (IHC) marker that is expressed predominantly in visceral smooth muscle - in recognizing muscularis propria (MP) in transurethral resection (TUR) and matched cystectomy specimens and to compare the pattern of its expression in muscularis mucosae (MM) and MP in radical cystectomy specimens. METHODS: IHC staining for smoothelin was ... Read more