ghada_galal

Ghada Galal

Professor - Head of Tropical Medicine and Gastroenterology Department

Faculty of medicine

Address: Sohag, Egypt

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Publications Which contain the keyword: Chronic Hepatitis C


Correlation of Serum Alanine Transaminase Level and Virus Load to the Extent of Liver Damage in Patients with Chronic Hepatitis C
Introduction: Hepatitis C virus (HCV) infection is usually monitored by the level of alanine transaminase (ALT) and viral load. However, accumulating data indicate that these parameters are not always correlated with the disease progression. Aim of the Work: This study aims to evaluate the relationship between serum ALT, serum HCV-RNA titer and the degree of histopathological liver damage in patients ... Read more

2018-09-15 12:29:30 Keywords Bridging fibrosis, Chronic Hepatitis C,
Clinical Utility of Simple Fibrosis Markers in Prediction of  Oesophageal Varices in Chronic Hepatitis C Patients with Advanced Fibrosis
_Background and Aims:_ Oesophageal varices (OV) are the most common complication of liver cirrhosis. However, no available data exist on the prevalence and the laboratory predictors of OV in chronic hepatitis C (CHC) Egyptian patients with bridging fibrosis or cirrhosis. Therefore, we aimed to investigate the frequency of OV in these patients and to assess whether simple non-invasive serum fibrosis ... Read more

2018-09-15 12:31:24 Keywords Chronic Hepatitis C, Liver Fibrosis,
Non-Invasive Assessment Of Liver Fibrosis In Chronic Hepatitis C Patients
BACKGROUND: The gold standard for assessment of liver fibrosis is liver biopsy, which is invasive and may rarely results in complications. Therefore, searching for alternative, accurate non-invasive parameters to evaluate the presence and degree of liver fibrosis is needed for prediction of prognosis and planning treatment of chronic hepatitis C (CHC) patients. AIM: To examine if serum laboratory markers combined ... Read more

The Role of Hepatic Progenitor Cells (HPCs) and the Predictors of Sustained Virological Response (SVR) to Interferon Therapy in Chronic Hepatitis C Infected Patients
ABSTRACT BACKGROUND: Studying the predictors of SVR to pegylated interferon (PEG-INF) alfa-2a and ribavirin (RBV) therapy in chronic hepatitis C-infected patients is crucial for selecting those who would benefit from therapy. Increasing HPCs in hepatitis C-infected patients were shown to be correlated with increased fibrosis and response to therapy. HPCs could be detected in the liver by immunohistochemical expressions of ... Read more

Serum Prohepcidin, Iron and Hepatic Iron Status in Chronic Hepatitis C in Egyptian Patients
Abstract Background/Aims: Patients with chronic hepatitis C (CHC) often have increased liver iron. Hepcidin has recently emerged as a key regulator for iron homeostasis. Therefore, we aimed to study the relationship between serum prohepcidin, serum iron indices, hepatic necro-inflammation, fibrosis and hepatic iron density and to determine the predictors of advanced fibrosis in those patients. Subjects and methods: Fifty CHC ... Read more

Non-Invasive Assessment of Liver Fibrosis in Chronic Hepatitis C Patients
BACKGROUND: The gold standard for assessment of liver fibrosis is liver biopsy, which is invasive and may rarely results in complications. Therefore, searching for alternative, accurate non-invasive parameters to evaluate the presence and degree of liver fibrosis is needed for prediction of prognosis and planning treatment of chronic hepatitis C (CHC) patients AIM: To examine if serum laboratory markers combined ... Read more

Metabolic Factors Associated with Hepatic Steatosis and Fibrosis in Patients with Chronic Hepatitis C
OBJECTIVE: Hepatic steatosis is a common histological feature in chronic hepatitis C (CHC), but its pathogenic mechanisms are not completely understood. We aimed to evaluate the metabolic factors associated with hepatic steatosis and fibrosis in CHC patients, and the relation between metabolic syndrome (MS) and CHC PATIENTS AND METHODS: This study included 71 patients with chronic HCV infection who underwent ... Read more