amr_ali

Amr Abdelhamed Ali Yousef

Lecturer - Lecturer, Department of Dermatology, Venereology & Andrology

Faculty of medicine

Address: Faculty of Medicine, Sohag University.

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Publications Which contain the keyword: Oxidative stress


2018-10-12 08:30:16 Keywords breast cancer, Egyptian Females, Oxidative stress, Soluble Fas.,
Correlations of circulating levels of oxidants, antioxidants and soluble Fas in breast cancer among Egyptian females
Background: Breast cancer is the first most common malignancy in Egyptian females. Oxidative stress is considered to be involved in the pathophysiology of all cancers, especially breast cancer. An inappropriately low rate of apoptosis can give rise to cancer. Objectives: The purpose of this study was to asses, compare and correlate the circulatory levels of some oxidants (malondialdehyde "MDA" and ... Read more

The benefit of a supplement with the antioxidant melatonin on redox status and muscle damage in resistance-trained athletes
Previous data showed that the administration of high doses of melatonin improved the circadian system in athletes. Here, we investigated in the same experimental paradigm whether the antioxidant properties of melatonin has also beneficial effects against exercise-induced oxidative stress and muscle damage in athletes. Twenty-four athletes were treated with 100 mg.day-1 of melatonin or placebo 30 min before bedtime during ... Read more

2018-10-07 22:13:52 Keywords ORP, semen, Oxidative stress, cryopreservation,
High seminal oxidation reduction potential in cryopreserved semen from infertile men is a marker of poor post-thaw sperm quality
OBJECTIVE Cryopreservation causes deleterious effects on human spermatozoa due to freezing and thawing, leading to decreased cryosurvival rates (CSR). The objectives of this study were to assess levels of oxidation-reduction potential (ORP) in cryopreserved semen of infertile men, and to determine their relationship to post-thaw sperm parameters. DESIGN A prospective cohort study. MATERIALS AND METHODS The study included 28 semen ... Read more

2018-10-08 22:37:04 Keywords Acrosome, MDA, Oxidative stress, Sperm, Infertility,
Oxidative stress and acrosomal morphology: A cause of infertility in patients with normal semen parameters
INTRODUCTION: Acrosome has a vital role in the process of penetration of zona pellucid (ZP). It is highly susceptible to elevated reactive oxygen species (ROS) and oxidative stress (OS). As generally accepted that OS stress has deteriorating effects on sperm functions, we studied the effect of OS on sperm parameters and acrosomal structure in infertile patients with normal semen parameters. ... Read more

2018-09-29 18:36:40 Keywords ultrastructure, tamoxifen, Oxidative stress, L-carnitine, iOAT,
Efficacy of Tamoxifen and L- carnitine on Sperm Ultrastructure and Seminal Oxidative Stress in patients with idiopathic Oligoasthenoteratozoospermia.
Idiopathic oligoathenoteratozoospermia (iOAT) is a common finding in the evaluation of male infertility. Oxidative stress (OS) may underlie its pathology. Tamoxifen and L-carnitine are used to treat idiopathic male infertility. The aim of this work was to detect the efficacy of tamoxifen and L-carnitine on sperm parameters, sperm ultrastructure and seminal OS in iOAT patients. Sixty patients were recruited for ... Read more

2018-09-29 19:03:01 Keywords Acrosome, MDA, Oxidative stress, Sperm, Infertility,
Oxidative stress and acrosomal morphology: A cause of infertility in patients with normal semen parameters
Introduction: Acrosome has a vital role in the process of penetration of zona pellucida (ZP). It is highly susceptible to elevated reactive oxygen species (ROS) and oxidative stress (OS). As generally accepted that OS stress has deteriorating effects on sperm functions, we studied the effect of OS on sperm parameters and acrosomal structure in infertile patients with normal semen parameters. ... Read more

2018-09-29 20:09:32 Keywords OAT, Sperm, Oxidative stress, Reactive oxygen species,
Oxidative stress and epididymal sperm transport, motility and morphological defects
Objectives: Radical oxidative species (ROS) have an important effect on sperm quality and quantity. Oxidative stress (OS) occurs when production of potentially destructive reactive oxygen species (ROS) exceeds the body’s own natural antioxidant defenses, resulting in cellular damage. OS is a common pathology seen in approximately half of all infertile men. Increased ROS generation and reduced antioxidant capacity is negatively ... Read more

2018-09-29 20:55:34 Keywords spermatozoa, Oxidative stress, nuclear DNA, male infertility,
Negative effects of increased sperm DNA damage in relation to seminal oxidative stress in men with idiopathic and male factor infertility
OBJECTIVE: To examine the effects of increased sperm DNA damage in relation to seminal oxidative stress in men with idiopathic and male factor infertility. DESIGN: Prospective study. SETTING: Infertility clinic at a tertiary care academic institution. PATIENT(S): Ninety-two infertile men with normal female partners. Sixteen fertile donors served as the control group. INTERVENTION(S): Standard semen analysis and assessment of levels ... Read more

Leukocytospermia is associated with increased   reactive oxygen species production by human spermatozoa.
OBJECTIVE: To investigate the role of increased seminal leukocytes in enhancing reactive oxygen species (ROS) production by human spermatozoa. DESIGN: A prospective study. SETTING: Male infertility clinic. PATIENT(S): Forty-eight infertile men. INTERVENTION(S): Standard semen analysis. Assessment of sperm nuclear DNA damage by sperm chromatin structure assay. Incubation of spermatozoa from nonleukocytospermic samples with blood neutrophils. MAIN OUTCOME MEASURE(S): Spontaneous and ... Read more

2018-09-19 15:34:32 Keywords Aging, angiogenesis, Oxidative stress, apoptosis.,
Oxidative Stress, Angiogenesis and Apoptosis in Relation to Aging
ABSTRACT Apoptosis and aging are complementary and cooperative processes that reduce cell proliferation and promote resistance to tumor development. Cellular levels of oxidative stress increase during physiological aging and tend to induce apoptosis, thereby influencing cellular and tissue aging and life span. Aim of study: is to determine the relationship between aging and apoptotic indices in the form of s-Fas ... Read more