essameldin_nada

Essameldin Abdelaziz Mohamed Ahmed Nada

Professor - Prof. of Dermatology,Venereology and Andrology

Faculty of medicine

Address: 8 Abou Bakr ElSedik Dokki Giza

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Publications Which contain the keyword: Oxidative stress


Endogenous and Exogenous Modulation of Nrf2 Mediated Oxidative Stress Response in Bovine Granulosa Cells: Potential Implication for Ovarian Function
Nrf2 is a redox sensitive transcription factor regulating the expression of antioxidant genes as defense mechanism against various stressors. The aim of this study is to investigate the potential role of noncoding miRNAs as endogenous and quercetin as exogenous regulators of Nrf2 pathway in bovine granulosa cells. For this cultured granulosa cells were used for modulation of miRNAs (miR-28, 153 ... Read more

Outer dense fibers abnormalities in spermatozoa of IOAT patients and their relation to oxidative stress and sperm motility
INTRODUCTION & OBJECTIVES: Human Spermatozoa are characterized by certain features that differentiate them from simple Flagella. One of these features is the presence of outer dense fibers (ODFs). ODFs are nine fibers surrounding Axoneme in the midpiece and extend to variable length through the principal piece. They represent about 30% of the protein portion of human spermatozoa and accordingly they ... Read more

2018-10-31 07:20:42 Keywords acne vulgaris, Oxidative stress,
oxidative stress indices in patients with acne vulgaris.
Background Acne vulgaris is a common dermatological disease frequently found in late childhood and adolescence. Oxidative stress corresponds to an imbalance between the rate of oxidant production and that of their degradation. Excessive rcactix c oxy gen species (ROS) production may explain, at least in part, the progress or inflammation in the pathogenesis or the disease. Objective "".'"1 assess tissue ... Read more

Lipid mobilization, insulin resistance and oxidative stress as metabolic adaptation processes in dairy cows during the periparturient period
This study aimed to evaluate several biochemical changes in dairy cows during the periparturient period. It was carried out on 38 multiparous Holstein/Friesian crossbreed dairy cows 3-11 years old. On the basis of clinical examination and assessment of BHBA concentration in blood, cows were classified to 4 groups, control healthy cows include 16 animals, subclinical ketosis include 10 animals, cows ... Read more

2018-10-27 23:06:47 Keywords Oxidative stress, acne vulgaris,
Assessment of oxidative stress indices in patients with acne vulgaris.
OBJECTIVE: To assess tissue levels of oxidative stress indices: Malondialdehyde (MDA) as free and antioxidants as superoxide dismutase (SOD) and catalase (CAT) in a group of patients with acne as compared to a control group. Also, to determine the relationship of oxidative stress indices with severity of acne .PATIENTS AND METHODS: Two punch biopsies (3 mm) were taken from the ... Read more

2018-10-22 23:44:33 Keywords Oxidative stress, (iOAT), Mitochondrial Anomalies, Midpiece,
Oxidative Stress in idiopathic Oligoathenoteratozoospermia (iOAT) and its Relation to Midpiece and Mitochondrial Anomalies.
INTRODUCTION AND AIM OF THE STUDY Idiopathic Oligoathenoteratozoospermia (iOAT syndrome) can be found in a high percentage of patients with male infertility. Reactive oxygen species (ROS) have been implicated in male infertility in the last years. In the present study we measured the levels of Reactive oxygen species (ROS) and Oxidative stress (OS) in iOAT patients and their correlation with ... Read more

Improving drought and salinity tolerance in barley by application of salicylic acid and potassium nitrate
Growth and physiological activities of barley (_Hordeum vulgare_ L. cv. Gustoe) grown in soil cultures were evaluated to recognize the ameliorative role of salicylic acid (SA) and KNO3 against the negative effects of salt and water deficit stresses. Barley plants were subjected to three levels of NaCl (50, 100 and 150 mM), three levels of water stress (80%, 70% and ... Read more

Melatonin, clock genes and mitochondria in sepsis
After the characterization of the central pacemaker in the suprachiasmatic nucleus, the expression of clock genes was identified in several peripheral tissues including the immune system. The hierarchical control from the central clock to peripheral clocks extends to other functions including endocrine, metabolic, immune, and mitochondrial responses. Increasing evidence links the disruption of the clock genes expression with multiple diseases ... Read more

Oxidative stress and sperm motility in spermatoozoa of IOAT patients and their relation to outer dense fibers abnormalities
INTRODUCTION AND OBJECTIVE: Outer dense fibers (ODFs) are nine fibers surrounding Axoneme in the midpiece and extend to variable length through the principal piece of spermatozoa. They represent about 30% of the protein portion of human spermatozoa and accordingly they are affected by any pathology that can affect protein content of spermatozoa as in presence of oxidative stress (OS). ODFs ... Read more

2018-10-15 23:54:11 Keywords Infertility, Oxidative stress, Semen analysis, varicocele,
Efficacy of medical treatment in varicocele patients presenting with oligoasthenoteratozoospermia
BACKGROUND: Varicocele is the most common cause of male infertility. It affects spermatogenesis by multiple theories; the most recent is by increasing the levels of reactive oxygen species. Medical treatment in the form of tamoxifen, anti-oxidant (Zinc) and MPFF (Micronised purified flavonoid fractions), may improve spermatogenesis and semen parameters in patients with varicocele. AIM: show the efficacy of medical treatment ... Read more