eman_shalabi

Eman Muhammad Salah El-Deen Muhammad Shalabi

Professor - Professor Emeritus of Pathology

Faculty of medicine

Address: القوصية - محافظة أسيوط

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Publications Which contain the keyword: E-cadherin


2020-09-05 20:24:15 Keywords E-cadherin, Breast Carcinoma,
Immunohistochemical Expression of E-cadherin in Invasive Duct Carcinoma of the Breast.
Breast cancer is the most frequent malignant tumor in women worldwide. E-Cadherin is a calcium-dependent epithelial cell adhesion molecule that is expressed at adherens junctions. Its loss may result in a poorly differentiated tumorphenotype. Cells with mutated E-cadherin demonstrate increased motility,altered organization of their actin cytoskeletonandassociated with metastases, thereby providing evidence for its role as an invasion suppressor. Objectives:Assess the ... Read more

2018-09-27 22:51:59 Keywords Endometrium, CD10 expression, E-cadherin,
P0070 E-cadherin and CD10 expression in atypical hyperplastic and malignant endometrial lesions
BACKGROUND Loss of E-cadherin is a critical step for development and progression of malignant tumours. CD10, a marker of non-neoplastic and neoplastic endometrial stroma, is associated with aggressiveness of many epithelial malignancies. We sought to evaluate the expression and correlation of E-cadherin and CD10 in endometrial lesions and their possible role in differentiating atypical endometrial hyperplasia from endometrial carcinoma. The ... Read more

E-cadherin and CD10 expression in atypical hyperplastic and malignant endometrial lesions
BACKGROUND: Loss of E-cadherin is a critical step for development and progression of malignant tumors. CD10; a marker of non-neoplastic and neoplastic endometrial stroma, is associated with aggressiveness of many epithelial malignancies. AIMS: To evaluate expression and correlation of E-cadherin and CD10 in endometrial lesions and their possible role in differentiating atypical endometrial hyperplasia from endometrial carcinoma. The association of ... Read more