khalaf.ali

Khalaf Ali Fayez Abuamra

استاذ - أستاذ متفرغ

كلية العلوم

العنوان: قسم النبات والميكروبيولوجى -كلية العلوم -جامعة سوهاج

2

إعجاب

المنشورات و المؤلفات التي تحتوي علي الكلمة المفتاحية: antibacterial


2019-11-25 08:49:32 الكلمات المفتاحية Molecular docking, Urease inhibitors, antibacterial, Oxadiazole, Ciprofloxacin,
Antibacterial and Urease Inhibitory activity of New Piperazinyl N-4 Functionalized Ciprofloxacin-oxadiazoles
This research includes design of new ciprofloxacin bearing oxadiazole at the N-4 piperazinyl for the purpose of having urease inhibitory activity as well as antibacterial activity. Hence, a group of new N-4 piperazinyl oxdiazole derivatives of ciprofloxacin was prepared and characterized using different spectroscopic and analytical techniques including 1H-NMR, 13C-NMR, MS and elemental analysis. Compounds 5b and 5c experienced moderate ... إقراء المزيد

2018-11-28 14:29:32 الكلمات المفتاحية imino-complexes, Hydrophilic, antibacterial,
Kinetics of acid hydrolysis and reactivity of some antibacterial hydrophilic Iron(II) imino-complexes
Kinetic study of acid hydrolysis of some hydrophilic Fe(II) Schiff base amino acid complexes with antibacterial properties was performed using spectrophotometry. The Schiff base ligands were derived from sodium 2-hydroxybenzaldehyde-5-sulfonate and glycine, L-alanine, L-leucine, L-isoleucine, DL-methionine DL-serine, or L-phenylalanine. The reaction was studied in aqueous media under conditions of pseudo-first order kinetics. Moreover, the acid hydrolysis was studied at different ... إقراء المزيد

2018-11-27 22:52:23 الكلمات المفتاحية Schiff base complexes, binary solvents, antibacterial,
Hydrophilicity and acid hydrolysis of water-soluble antibacterial Iron(II) Schiff base complexes in binary aqueous solvents
Kinetics of acid hydrolysis of seven antibacterial iron(II) Schiff base complexes has been studied. The Schiff base ligands were derived from sodium 2-hydroxybenzaldehyde-5-sulfonate and a series of amino acids. The hydrolysis rate is studied by spectrophotometric method and compared with complex hydrophilicity. Addition of the organic co-solvent, dimethylsulfoxide or n-propanol, significantly accelerates the hydrolysis. إقراء المزيد

2018-11-28 14:29:32 الكلمات المفتاحية antibacterial, ONO donors, Hydrophobicity,
DNA binding ability mode, spectroscopic studies, hydrophobicity, and in vitro antibacterial evaluation of some new Fe(II) complexes bearing ONO donors amino acid Schiff bases
New series of Fe(II) complexes and Schiff base amino acids have been designed and synthesized from the bioactive ligands by condensation of 5-bromo-2-hydroxybenzaldehyde and aamino acids (L-alanine (ala), L-phenylalanine (phala), L-aspartic acid (aspa), L-histidine (his) and L-arginine (arg)). Elemental analyses, infrared, ultraviolet–visible spectra, as well as conductivity and magnetic susceptibility measurements are used to elucidate the structure of the newly ... إقراء المزيد

2018-09-16 14:32:30 الكلمات المفتاحية Schiff base, amino acid, Fe(II), Teratogenicity, DNA interaction, antibacterial, Antifungal, high spin, Design, IR,
Design, characterization, teratogenicity testing, antibacterial, antifungal and DNA interaction of few high spin Fe(II) Schiff base amino acid complexes
In this study, new Fe(II) Schiff base amino acid chelates derived from the condensation of o-hydroxynaphthaldehyde with l-alanine, l-phenylalanine, l-aspartic acid, l-histidine and l-arginine were synthesized and characterized via elemental, thermogravimetric analysis, molar conductance, IR, electronic, mass spectra and magnetic moment measurements. The stoichiometry and the stability constants of the complexes were determined spectrophotometrically. Correlation of all spectroscopic data suggested ... إقراء المزيد

2018-09-06 08:53:59 الكلمات المفتاحية antibacterial, Binding constant, Calf thymus DNA, Fe(II) complexes, Hydrophobicity, amino acid,
DNA binding ability mode, spectroscopic studies, hydrophobicity, and in vitro antibacterial evaluation of some new Fe(II) complexes bearing ONO donors amino acid Schiff bases
New series of Fe(II) complexes and Schiff base amino acids have been designed and synthesized from the bioactive ligands by condensation of 5-bromo-2-hydroxybenzaldehyde and α-amino acids (l-alanine (ala), l-phenylalanine (phala), l-aspartic acid (aspa), l-histidine (his) and l-arginine (arg)). Elemental analyses, infrared, ultraviolet–visible spectra, as well as conductivity and magnetic susceptibility measurements are used to elucidate the structure of the newly ... إقراء المزيد

2018-10-30 09:21:08 الكلمات المفتاحية antibacterial, Fused Azoles, Oxazinones,
" Synthesis and Antibacterial of Certain Fused Azoles and Oxazinones
Synthesis and Antibacterial of Certain Fused Azoles and Oxazinones إقراء المزيد

2018-09-10 12:57:58 الكلمات المفتاحية Triazolotriazoles;, Oxadiazolotriazoles;, antibacterial,
“Synthesis and Antibacterial Activity of Some New 4-anilino-5-phenyl-4H-1,2,4-triazole-3-thiol derivatives
4-Anilino-5-phenyl-4H-1,2,4-triazole-3-thiol (1) reacted with formaldehyde and different amines to give Mannich bases 2a–i. Treatment of compound 1 with formaldehyde afforded the corresponding 2-hydroxymethyl derivative 3, which upon its reaction with thionyl chloride yielded the corresponding chloromethyl derivative 4. Treatment of compound 4 with some thiols gave the corresponding sulfides 5a–f. The ring closure reaction of chloromethyl derivative 4 with hydrazine ... إقراء المزيد

2018-09-10 12:54:57 الكلمات المفتاحية Pyridines, thiophenes, thienopyridines, antibacterial, anti-inflammatory,
Synthesis, in vitro Antibacterial and in vivo Anti-inflammatory Activity of Some New pyridines
Reaction of 4,6-diamino-3-cyano-2-methylthiopyridine (I) with chloroacetyl chloride or acetic acid afforded the corresponding 6-acetamide derivatives IIa and IIb, respectively. Chloroacetamide derivative IIa reacted with various thiols, secondary amines, potassium thiocyanate, compounds containing active methylene group,1-anilino-2,2-dicyanoethenethiolate, and o-mercatocyanopyridines to give S-alkyl, N-alkyl, thiazole, pyrrole, thiophene, and thienopyridine derivatives, respectively. Antibacterial and anti-inflammatory activities of some new pyridine derivatives were studied. إقراء المزيد

2018-10-16 18:18:07 الكلمات المفتاحية antibacterial, ANTIOXIDANT, Balanites aegyptiaca,
Antibacterial and Antioxidant Activities of Balanites aegyptiaca Kernel and Its Effects on Ccl4 Treated Rats.
* Fatmaa A. A. Mostafa; Afaf Ali; W. H. M. Elreffaei ; Rasha A. Shalabyand, A. E. MEHANNI. Antibacterial and Antioxidant Activities of Balanites aegyptiaca Kernel and Its Effects on Ccl4 Treated Rats. J. Food and Dairy Sci., Mansoura Univ., Vol. 7(10): 407 - 414 , 2016. إقراء المزيد