Use of PTEN, PCNA, and β-catenin to differentiate between endometrial hyperplasia and endometrial adenocarcinoma
Background The use of PTEN, PCNA, and β-catenin may be of value to differentiate well differentiated endometrioid carcinoma from complex atypical endometrial hyperplasia. Methods Immunohistochemical evaluation of PTEN, PCNA, and β-catenin was performed on 100 specimens including eight proliferative endometrium, 10 secretory endometrium, 10 simple endometrial hyperplasia, 10 complex typical endometrial hyperplasia, 30 complex atypical endometrial hyperplasia, and 32 endometrioid ... Read more