ahmedabudief

Dr. Ahmed Mohammed Abu-Dief Mohammed

Assistant Professor - Assistant professor of Inorganic and Physical Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street

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Publications Which contain the keyword: TGA


Design, Characterization, DNA Interaction and antimicrobial of novel copper(II) Schiff base amino acid complexes
Five novel copper(II) complexes derived from the condensation between 5-bromosalicyaldhyde (bs) and α-amino acids (L-alanine, L-phenylalanine, L-aspartic acid, L-histidine and L-arginine) were synthesized and characterized by their elemental analyses, thermogravemetric analysis, IR, electronic spectra and conductance and magnetic measurements. Moreover, the stoichiometry and the stability constants of the prepared complexes have been determined spectrophotometrically. The Results indicated that the Schiff ... Read more

Metal based pharmacologically active agents: Synthesis, structural characterization, molecular modeling, CT-DNA binding studies and in vitro antimicrobial screening of iron(II) chelates
In recent years, great interest has been focused on Fe(II) Schiff base amino acid complexes as cytotoxic and antitumor drugs. Thus a series of new iron(II) complexes based on Schiff bases amino acids ligands have been designed and synthesized from condensation of 5-bromosalicylaldehyde (bs) and α-amino acids (l-alanine (ala), l-phenylalanine (phala), l-aspartic acid (aspa), l-histidine (his) and l-arginine (arg)). The ... Read more

Physicochemichal properties, DNA interaction, antiviral and antioxidant activities of some Amino Acid Imine Chelates
Schiff base amino acid ligands which derived from the condensation of 3-methoxysalicylaldehyde (MS) or 4-diethylaminosalicylaldehyde (DS) with some of α-amino acids (Phenylalanine (Phe), Histidine (His), Tryptophan (Trp)) were prepared. Moreover, eleven Schiff base amino acid binary Fe(II) and Cu(II) complexes were prepared. In addition to, five ternary Cu(II) complexes which derived from the prepared Schiff base amino acid ligands as ... Read more

Synthesis, structure elucidation, biological screening, molecular modeling and DNA binding of some Cu(II) chelates incorporating imines derived from amino acids
Three tridentate Schiff bases amino acids were prepared by direct condensation of 3-methoxysalicylaldehyde (MS) or 4-diethylaminosalicylaldehyde (DS) with α-amino acid ligands [l-phenylalanine (P), l-histidine (H) and DL-tryptophan (T)]. The prepared Schiff bases amino acids were investigated by melting points, elemental analysis, 1HNMR and 13CNMR, IR, UV–Vis spectra, conductivity and magnetic measurements analyses. Subsequently, copper was introduced and Cu(II) complexes formed. ... Read more

Sonochemical synthesis, DNA binding, antimicrobial evaluation and in vitro anticancer activity of nano-sized Cu(II), Co(II) and Ni(II) chelates  as precursors for metal oxides
Three new nano sized Cu(II), Co(II) and Ni(II) complexes of imine ligand derived from the condensation of 2-amino-3-hydroxypyridine and 3-methoxysalicylaldehyde have been prepared and investigated using various chemical techniques such as NMR, elemental analysis, molar conductance, IR, electronic spectra, TGA and magnetic momentmeasurements. The obtained chemical analysis data showed that the synthesis of 1:1 (metal:ligand) ratio and octahedral geometry was ... Read more

Some new nano-sized Cr(III), Fe(II), Co(II), and Ni(II) complexes: Structural characterization, electrochemical, antioxidant, antimicrobial, antiviral assessment and DNA interaction
To estimate the biological preference of synthetic small drugs towards DNA target, new metal based chemotherapeutic agents of nano-sized Cr(III), Fe(II), Co(II) and Ni(II) Schiff base complexes having N,N,O donor system were synthesized and thoroughly characterized by physic-chemical techniques. The redox behavior of the Cr(III), Fe(II) and Co(II) complex was investigated by electrochemical method using cyclic voltammetry. IR results proven ... Read more

2018-10-01 14:02:38 Keywords Pharmaceutical, Oxides, nanoparticles, Imine complexes, TGA,
Pharmaceutical Applications of Nano Imine Complexes and Their Oxides
Some new nano-sized Mn(II), Fe(II), Co(II), Ni(II), Cu(II), Cd(II), Zn(II),, Pb(II) and Ag(I) complexes with imine ligands derived from 2-amino-3-hydroxypyridine (ahp) and 3-methoxysalicylaldehyde (v) or 4-nitrobenzaldehyde (nb) were prepared by sonochemical method. Melting point, decomposition temperature, infrared (IR) and NMR spectra, elemental analyses, conductance and magnetic susceptibility measurements, TG and UV – Visible spectrophotometric studies were utilized in characterizing of ... Read more

2018-10-01 13:52:36 Keywords TGA, Nano imine Chelates, DNA binding, Biological Applications,
Some Nano imine Chelates for DNA Binding and Biological Applications
Air and moisture stable coordination compounds of some first transition metals such as Cr (III), Fe (II), Co(II), Ni(II) and Cu(II) with newly designed tri and tetra-dentate imine ligands ( bsap, npap, bsisnph, npisnph) were synthesized. Tridentate imine ligands (bsap, npap) were synthesized by reacting 5-bromosalicyaldehyde (bs) or 2-hydroxy-1-napthaldehyde (np) with 2-aminopyridine (ap), whereas tetra-dentate imine ligands (bsisnph, npisnph) were ... Read more

Ni(II) and Cu(II) complexes : synthesis, spectroscopic characterization, theoretical calculations, DNA interaction and antimicrobial studies
A novel Schiff base, namely _Z_‐3‐((2‐((_E_)‐(2‐hydroxynaphthyl)methylene)amino)‐5‐nitrophenylimino)‐1,3‐dihydroindin‐2‐one, was synthesized from the condensation of 2‐hydroxy‐1‐naphthaldehyde and isatin with 4‐nitro‐_o_‐phenylenediamine. It was structurally characterized on the basis of 1H NMR, 13C NMR and infrared spectra and elemental analyses. In addition, Ni(II) and Cu(II) complexes of the Schiff base ligand were prepared. The nature of bonding and the stereochemistry of the investigated complexes were ... Read more

Development, structural investigation, DNA binding, antimicrobial screening and anticancer activities of two novel quari-dentate VO(II) and Mn (II) mononuclear complexes
Two novel VO(II) and Mn(II) imine chelates derived from the condensation of o-phenylenediamine (PN) with 3-ethoxysalicylaldehyde(ES) were synthesized. The prepared ESPN imine ligand and its chelates were investigated _via_ different analytical and physicochemical tools. Correlation between all the obtained results, the parent ligand behaves as tetra-dentate ONNO ligand and coordinates to Mn(II) and VO(II), in octahedral and square pyramidal geometry, ... Read more