ahmedabudief

Dr. Ahmed Mohammed Abu-Dief Mohammed

Assistant Professor - Assistant professor of Inorganic and Physical Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street

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Publications Which contain the keyword: DNA interaction


Some New  Ag(I),  VO(II)  and Pd(II) Chelates encompassing Tri-dentate Imine Ligand: Design, synthesis, Structure elucidation and DFT calculations for DNA Interaction, Antimicrobial, Anticancer Activities and Molecular Docking Studies
Some new complexes derived from VO(II), Ag(I) and Pd(II) metal ions and HNA imine ligand (L) _i.e. _(2-[(6-Allylidene-2-hydroxy-cyclohexa-1,3-dienylmethylene)-amino]-benzoic acid) have been prepared and their structures are elucidated _via_ molar conductance, elemental analyses, IR, NMR, magnetic susceptibility estimations and electronic spectral studies. Moreover, stability constants of the synthesized complexes were evaluated utilizing spectrophotometric technique. On the basis of molar conductance and ... Read more

Approach to Synthesis, Characterization, Antimicrobial Activities and Catalytic Activity of Some Transition Metal Complexes Containing Biologically Active Asymmetrical Tetradentate Ligands.
AIR AND MOISTURE STABLE COORDINATION COMPOUNDS OF FIRST TRANSITION METALS SUCH AS CO(II), NI(II) AND CU(II) WITH NEWLY DESIGNED SCHIFF BASE (BSIPH) INCORPORATING 5-BROMOSALICYALDEHYDE WITH ISATIN AND 4-NITRO-O-PHENYLENE DIAMINE HAVE BEEN SYNTHESIZED TO ELUCIDATE THE STRUCTURE OF METAL COMPLEXES. THEY ARE CHARACTERIZED BY ELEMENTAL ANALYSES, INFRARED, 1HNMR, 13CNMR, THERMAL ANALYSIS, UV-VISIBLE, CONDUCTIVITY AND MAGNETIC SUSCEPTIBILITY MEASUREMENTS. THE RESULTS SUGGEST THAT ... Read more

Complexation of Schiff bases incorporating of Salicylaldehyde Derivatives and Amino Acids to Copper(II) as an effective strategy for antimicrobial activity improvement, DNA Interaction and catalytic activity
Five Cu(II) complexes are tridentate Schiff bases amino acids ligands derived from condensation 3–methoxysalicylaldehyde (MS) or 4-diethylaminosalicylaldehyde (DS) with α-amino acids (L-phenylalanine(P), L-histidine (H), DL-tryptophane (T)). All ligands are analyzed by 1HNMR and 13CNMR. The investigated complexes have been prepared and characterized by elemental analysis, infrared spectra, ultraviolet-visible and thermal analysis in dynamic air atmosphere (40ml / min) at a ... Read more

Design, Synthesis, anticancer activity and molecular docking studies on a series of VO(II), Cr (III), Mn(II) and Ni(II) Mononuclear Chelates incorporating Quaridentate imine ligand as antitubulin agents
The present study was conducted to synthesis of some new imine Cr(III), VO(II), Mn(II) and Ni(II) complexes derived from the condensation of 2-amino phenol with 2-hydroxynapthaldehyde were synthesized. The prepared HNPN imine ligand was analyzed by its melting point, IR, 1H NMR and 13C NMR spectroscopies. The investigated HNPN imine complexes were characterized by elemental analysis, FT IR, Uv-vis and ... Read more

Synthesis, characterization, DNA cleavage and antimicrobial activity of Schiff base transition metal complexes containing heterocyclic ligand
SOME NOVEL SCHIFF BASE METAL COMPLEXES OF CU(II), CO(II), NI(II) AND FE(II) DERIVED FROM 2-AMINO-3-HYDROXYPYRIDINE AND 4-NITROBENZALDEHYDE WERE SYNTHESIZED. THESE COMPOUNDS WERE CHARACTERIZED BY ELEMENTAL ANALYSIS, MOLAR CONDUCTANCE, MAGNETIC SUSCEPTIBILITY, THERMAL MEASUREMENTS, INFRARED AND ULTRAVIOLET–VISIBLE SPECTRA. THE SCHIFF BASE AND METAL COMPLEXES DISPLAYED GOOD ACTIVITY (AGAINST THE BACTERIA, _ESCHERICHIA COLI,__SERRATIA MARCESCENCE_AND_MICROCCUS LUTEUS_, AND THE FUNGI _ASPERGILLUS FLAVUS_, _GETRICHM CANDIDUM _AND ... Read more

Design, Characterization, DNA Interaction and antimicrobial of novel copper(II) Schiff base amino acid complexes
Five novel copper(II) complexes derived from the condensation between 5-bromosalicyaldhyde (bs) and α-amino acids (L-alanine, L-phenylalanine, L-aspartic acid, L-histidine and L-arginine) were synthesized and characterized by their elemental analyses, thermogravemetric analysis, IR, electronic spectra and conductance and magnetic measurements. Moreover, the stoichiometry and the stability constants of the prepared complexes have been determined spectrophotometrically. The Results indicated that the Schiff ... Read more

Design, Physicochemical Studies and DNA Interaction of Some Complexes
In recent years, great interest has been focused on Fe(II) Schiff bases amino acids complexes as cytotoxic and antitumor drugs. Thus a series of new iron(II) complexes based on Schiff bases amino acids ligands have been designed and synthesized from condensation of 2-hydroxy-1-naphthaldehyde and 5-bromosalicylaldehyde (bs) with α-amino acids ((L-alanine (ala), L-phenylalanine (phala), L-aspartic acid (aspa), L-histidine (his) and L-arginine ... Read more

Design, characterization, teratogenicity testing, antibacterial, antifungal and DNA interaction of few high spin Fe(II) Schiff base amino acid complexes
In this study, new Fe(II) Schiff base amino acid chelates derived from the condensation of o-hydroxynaphthaldehyde with l-alanine, l-phenylalanine, l-aspartic acid, l-histidine and l-arginine were synthesized and characterized via elemental, thermogravimetric analysis, molar conductance, IR, electronic, mass spectra and magnetic moment measurements. The stoichiometry and the stability constants of the complexes were determined spectrophotometrically. Correlation of all spectroscopic data suggested ... Read more

2018-09-16 14:36:08 Keywords Fe(II) complexes, Toxicity, DNA interaction, amino acid, Schiff base,
Synthesis, physicochemical studies, embryos toxicity and DNA interaction of some new Iron(II) Schiff base amino acid complexes
New Fe(II) Schiff base amino acid complexes derived from the condensation of o-hydroxynaphthaldehyde with l-alanine, l-phenylalanine, l-aspartic acid, l-histidine and l-arginine were synthesized and characterized by elemental analysis, IR, electronic spectra, and conductance measurements. The stoichiometry and the stability constants of the complexes were determined spectrophotometrically. The investigated Schiff bases exhibited tridentate coordination mode with the general formulae [Fe(HL)2]·nH2O for ... Read more

2018-10-01 14:10:56 Keywords Iron Complexes, DNA interaction, Hydrolysis, Kinetics,
Kinetics of Alkaline Hydrolysis and DNA Interaction of Iron Complexes
Air and moisture stable coordination compounds of some first transition metals such as Cr (III), VO (II), Ni(II) and Mn(II) with newly designed tri- and tetra-dentate imine ligands (HNAP, HNPN and ESPN) were synthesized. Tridentate imine ligands (HNAP, ESAP) were synthesized by reacting 2-hydroxynapthaldehyde (HN) with 2-aminophenol (AP), whereas tetra-dentate imine ligands (HNPN and ESPN) were prepared by reacting 2-hydroxy-1-napthaldehyde ... Read more