Khalaf Ali Fayez Abuamra

استاذ - أستاذ متفرغ

كلية العلوم

العنوان: قسم النبات والميكروبيولوجى -كلية العلوم -جامعة سوهاج



المنشورات و المؤلفات التي تحتوي علي الكلمة المفتاحية: DNA interaction

2019-10-19 14:22:17 الكلمات المفتاحية ANTIOXIDANT, Anticancer efficiency, Antimicrobial activity, Azomethine Chelates, DNA interaction,
A robust in vitro Anticancerc, Antioxidant and Antimicrobial Agents Based on New Metal-Azomethine Chelates Incorporating Ag(I),  VO(II)  and Pd(II) Cations: Probing the Aspects of DNA Interaction
A novel azomethine ligand (HNAP) [HNAP = 1-(Pyridin-3-yliminomethyl)-naphthalen-2-ol] and its Ag(I), Pd(II) and VO(II) chelates have been synthesized and structurally inspected using a wide range of spectroscopic and analytical tools, including infra-red (IR), ultraviolet-visible (UV-Vis) and 1H NMR spectroscopy techniques, CHN analysis, molar conductance, magnetic susceptibility, and thermogravimetric analysis. The molar conductance measurements reveal that the chelates are non-electrolytes. The ... إقراء المزيد

2019-08-09 10:54:55 الكلمات المفتاحية Imine complexes, DFT Calculations, Antimicrobial activity, DNA interaction, anticancer activity,
Novel Azomethine Pd(II) and VO(II)  Based Metallo-Pharmaceuticals as Anticancer, Antimicrobial and Antioxidant  agents:  Design, Structural inspection,  DFT investigation and DNA interaction
The new NO bi-dentate imine ligand namely (2-[(3-Nitro-benzylidene)-amino]-benzoic acid) (NBA) imine ligand (L) and their Pd(II) and VO(II) complexes have synthesized and characterized utilizing different physiochemical methods including elemental analyses, FT-IR, NMR, molar conductance and magnetic susceptibility measurements. The stability constant of these complexes has also determined. The studies of these complexes were found to have [M (L)] composition where ... إقراء المزيد

Fabrication, Spectroscopic Characterization, Calf thymus DNA Binding Investigation, Antioxidant and Anti-cancer Activities of Some Antibiotic Azomethine Cu(II), Pd(II), Zn(II) and Cr(III) Complexes
This study was conducted to prepare novel azomethine chelates of Cu(II), Pd(II), Zn(II) and Cr(III) with tri-dentate dianionic azomethine OVAP ligand 2-[(2-Hydroxy-phenylimino)-methyl]-6-methoxy-phenol. The prepared compounds were characterized with the help of elemental analyses, spectral (NMR, FT-IR, UV-vis, mass), conductivity, magnetic and thermal measurements. The spectroscopic data suggest that the parent azomethine ligand bind to the investigated metal ions through both ... إقراء المزيد

2018-11-27 23:00:21 الكلمات المفتاحية Embryos toxicity, Schiff base amino acid, DNA interaction,
Synthesis, physicochemical studies, embryos toxicity and DNA interaction of some new Iron(II) Schiff base amino acid complexes
New Fe(II) Schiff base amino acid complexes derived from the condensation of o-hydroxynaphthaldehyde with L-alanine, L-phenylalanine, L-aspartic acid, L-histidine and L-arginine were synthesized and characterized by elemental analysis, IR, electronic spectra, and conductance measurements. The stoichiometry and the stability constants of the complexes were determined spectrophotometrically. The investigated Schiff bases exhibited tridentate coordination mode with the general formulae [Fe(HL)2]nH2O for ... إقراء المزيد

2018-11-28 20:59:46 الكلمات المفتاحية DNA interaction, Base-catalyzed hydrolysis, Fe(II),
Reactivity trends and kinetic inspection of hydroxide ion attack and DNA interaction on some pharmacologically active agents of Fe(II) amino acid Schiff base complexes at different temperatures
The reactivity of few novel high-spin Fe(II) complexes of Schiff base ligands derived from 2-hydroxynaphthaldehyde and some variety of amino acids with the OH− ion has been examined in an aqueous mixture at the temperature range from 10 to 40°C. Based on the kinetic investigations, the rate law and a plausible mechanism were proposed and discussed. The general rate equation ... إقراء المزيد

2018-11-27 13:19:38 الكلمات المفتاحية Pd (II), Cu(II) Complexes, DNA interaction, Antimicrobial activity, Ag(I),
Design, Synthesis, Characterization and biological application of some new Schiff Base Cu(II), Pd(II) and Ag(I) Complexes
In this investigation, new Cu(II), Pd(II) and Ag(I) complexes with the tetra-dentate DSPH Schiff base ligand were synthesized. The DSPH Schiff base and its complexes were characterized by using different physicochemical and spectral analysis. The results revealed that the metal ions coordinated with DSPH ligand through azomethine nitrogen and phenolic oxygen. Cu(II), Pd(II) and Ag(I) complexes are present in a ... إقراء المزيد

2018-10-05 12:14:37 الكلمات المفتاحية amino acid, Nano Sized, Cu(II) complexes, DNA interaction, Salicylaldehyde Derivatives, TEM, IR, TGA, Conductivity,
Nano sized ternary Cu(II) complexes Encompassing Salicylaldehyde Derivatives and Amino Acids as an Effective Strategy for Antimicrobial Activity Improvement and DNA Interaction
A series of ternary Cu(II) complexes encompassing ONO donor Schiff base amino acid ligands were synthesized from condensation of 3–methoxysalicylaldehyde (MS) or 4-diethylamino salicylaldehyde (DS) with α-amino acids (L-phenylalanine (Phe), L-histidine (His), DL-tryptophan (Trp)) as primary ligand and 2, 4-bipridyl (DP) as secondary ligand. All the prepared compounds were characterized by melting points, decomposition temperatures, elemental analysis, UV-Vis, IR spectra, ... إقراء المزيد

2018-11-26 08:20:45 الكلمات المفتاحية DNA interaction, Antimicrobial activity, anticancer activity, complexes, Schiff base, VO(II), Pd (II),
New palladium (II) and silver (I) Schiff base complexes Promising antibiotic and anticancer agents
Some new complexes derived from Ag (I) and Pd(II) metal ions and HNA imine ligand (L) _i.e. _(2-[(6-Allylidene-2-hydroxy-cyclohexa-1,3-dienylmethylene)-amino]-benzoic acid) have been synthesized and characterized by elemental analyses, molar conductance, magnetic susceptibility measurements, IR, NMR and electronic spectral studies. Moreover, the stability constants of the synthesized complexes were determined spectrophotometrically. On the basis of molar conductance and elemental analyses the complexes ... إقراء المزيد

2018-11-25 17:26:51 الكلمات المفتاحية Synthesis, DNA interaction, DFT studies, Antimicrobial activity, IR, TGA, Imidazole Ligand,
Synthesis, Characterization and Biological Studies of Some new Cr(III), Fe(III) and Cu(II) Complexes based on Multi-Substituted  Aryl Imidazole ligand
New Cr (III), Fe (III) and Cu (II) complexes with MSBB (2‐(1‐butyl‐4,5 diphenyl‐1H‐imidazol‐2‐yl)(4-bromophenol) were synthesized. The multi-substituted aryl imidazole ligand (MSBB) and its complexes were characterized by using elemental and thermal analysis, molar conductivity, magnetic susceptibility, UV-Vis spectral data, IR, and NMR. The obtained data showed that prepared complexes were 1 :1 (metal : ligand) ratio, octahedral (Oh) for all ... إقراء المزيد

Some New  Ag(I),  VO(II)  and Pd(II) Chelates encompassing Tri-dentate Imine Ligand: Design, synthesis, Structure elucidation and DFT calculations for DNA Interaction, Antimicrobial, Anticancer Activities and Molecular Docking Studies
Some new complexes derived from VO(II), Ag(I) and Pd(II) metal ions and HNA imine ligand (L) _i.e. _(2-[(6-Allylidene-2-hydroxy-cyclohexa-1,3-dienylmethylene)-amino]-benzoic acid) have been prepared and their structures are elucidated _via_ molar conductance, elemental analyses, IR, NMR, magnetic susceptibility estimations and electronic spectral studies. Moreover, stability constants of the synthesized complexes were evaluated utilizing spectrophotometric technique. On the basis of molar conductance and ... إقراء المزيد