eman_shalabi

Eman Muhammad Salah El-Deen Muhammad Shalabi

Professor - Professor of Pathology

Faculty of medicine

Address: القوصية - محافظة أسيوط

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Publications Which contain the keyword: liver


2018-10-31 06:09:40 Keywords liver, TiO2, nanoparticles, milk thistle,
Ultrastructure, Histochemical and Biochemical effects of Titanium dioxide nanoparticles in Adult male albino rat liver and possible prophylactic effects of Milk thistle seeds
ABSTRACT: Nanotechnology refers to material at the nanometer scale. It has the commercial application of products in the fields of medicine, engineering, manufacturing, information and environmental technology. Titanium dioxide nanoparticles (Tio2 NPs) are manufactured worldwide in large quantities for use in a wide range of applications including pigments, plastics, papers, inks, food colorants, toothpastes and cosmetic manufacturing. Milk thistle is ... Read more

2018-10-28 06:30:32 Keywords Mycotoxin, patulin, liver, Rat,
2012 ,Biochemical and histological studies on the effect of the Patulin mycotoxin on male rats’ liver and treatment by crude venom extra,2012cted from jelly fish
Patulin mycotoxin on some biochemical parameters and histological changes on male rats' liver and effect of crude venom extracted from jelly fish Cassiopea Andromeda as a treatment. 50 Inbreeding weanling white male wistar lewis rats were divided randomly into 5 groups. Control group was gavage fed daily with distilled water; three treated groups were gavage fed daily dose with Patulin ... Read more

2018-09-24 18:01:53 Keywords CD34, liver,
CD34 Expression as a marker of progression of chronic hepatitis C
In Egypt, the rate of death/transplantation, decompensation and HCC in patients with compensated HCV cirrhosis is 4.58%, 6.37% and 3.36%, respectively. It is estimated that Egyptian patients with HCV cirrhosis had an annual incidence of HCC with 5.3%. CD34 is a 110-kDa transmembrane glycoprotein present on leukemic cells, endothelial cells and stem cells). CD34 is preferentially expressed on the surface ... Read more

2018-10-21 05:52:44 Keywords liver, Microcirculation,
Circulatory injury in liver transplantation
Optimum graft function after liver transplantation is dependent on adequate sinusoidal perfusion. Hepatic microcirculation may be compromised by sev- eral factors such as cold ischemia, quality of the liver graft, handling of the organ during surgery, surgical procedure, and reperfusion injury. This chapter will focus on the pathological consequences of cold preservation and reperfu- sion injury on hepatic microcirculation. Microcirculatory ... Read more

2018-10-21 05:41:41 Keywords liver, transplantation, Platel,
Low Platelet Counts After Liver Transplantation Predict Early Posttransplant Survival: The 60-5 Criterion
Platelets play a critical role in liver injury and regeneration. Thrombocytopenia is associated with increases in postoperative complications after partial hepatectomy, but it is unknown whether platelet counts could also predict outcomes after trans- plantation, a procedure that is often performed in thrombocytopenic patients. Therefore, the aim of this study was to evalu- ate whether platelet counts could be indicators ... Read more

2018-10-21 05:36:50 Keywords liver, Regeneration, serotonin,
Activation of Serotonin Receptor-2B Rescues Small-for-Size Liver Graft Failure in Mice
The implantation of grafts below 30% of the normal liver volume is associated with a high risk of failure known as small-for-size (SFS) syndrome. Strategies to rescue small grafts may have a dramatic impact on organ shortage. Serotonin is a potent growth factor for the liver. The goal of this study was to determine whether enhanced serotonin signaling could prevent ... Read more

2018-10-21 05:04:55 Keywords Regeneration, liver,
Selective Portal Vein Embolization and Ligation Trigger Different Regenerative Responses in the Rat Liver
Two strategies are clinically available to induce selective hypertrophy of the liver: portal vein emboli- zation (PVE) and portal vein ligation (PVL). The aim of this study was to compare the impact of PVE and PVL on liver regeneration. Rats were subjected to 70% PVL, 70% PVE, 70% partial hepatectomy (PH) (positive control), or sham operation (negative control). PVL and ... Read more

2018-10-21 04:58:56 Keywords liver, Steatosis, Transplantat,
When is steatosis too much for transplantation?
Steatosis is assessed according to the pattern and the amount of fatty infiltration in hepatic tissue sections. Traditionally, fatty accumulation has been classified morphologically as macrovesicular or microvesicular. Macrovesicular steatosis is characterised by a single, bulky fat vacuole in the hepatocyte that displaces the nucleus to the edge of the cell. Among a variety of dis- orders alcohol abuse, obesity, ... Read more

2018-10-21 04:54:52 Keywords transplantation, Fatty, liver,
Liver transplantation using fatty livers: Always feasible?
Steatotic liver grafts represent the most common type of ‘‘extended criteria’’ organs that have been introduced during the last two decades due to the disparity between liver transplant candidates and the number available organs. A precise definition and reliable and reproducible method for steatosis quantification is currently lacking and the potential influence of the chemical composition of hepatic lipids has ... Read more

2018-10-21 04:53:03 Keywords liver, Steatosis, Omega, Throm,
Chemical composition of hepatic lipids mediates reperfusion injury of the macrosteatotic mouse liver through thromboxane A2
Background & Aims: Chemical composition of hepatic lipids is an evolving player in steatotic liver ischemia/reperfusion (I/R) injury. Thromboxane A2 (TXA2) is a vasoactive pro-inflammatory lipid mediator derived from arachidonic acid (AA), an omega-6 fatty acid (X-6 FA). Reduced tolerance of the macrosteatotic liver to I/R may be related to increased TXA2 synthesis due to the pre- dominance of X-6 ... Read more