ahmedabudief

Dr. Ahmed Mohammed Abu-Dief Mohammed

Assistant Professor - Assistant professor of Inorganic and Physical Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street

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Publications Which contain the keyword: one-pot Multicomponent synthes


New Method for Synthesis of Multi-substituted Imidazoles
Here, we reported two methods for the synthesis of multi-substituted imidazoles,firstly via four-component cyclocondensation reaction of benzil, aliphatic amines (allylamine or pentylamine), and aromatic aldehyde and ammonium acetate. Using an ionic liquid catalyst namely, diethyl ammonium hydrogen sul-fate, and under solvent-free conditions. Secondly, via the alkylation of synthesized NH imidazoles with alkyl halide (allyl bromide and pentyl bromide) gave8a–cin high ... Read more

Efficient Protocol for the One-Pot Multicomponent Synthesis of Novel 2-Tosyloxyphenylpyrans and Schiff bases with Anti-inflammatory and Antioxidant Activities
1442One-PotMulticomponentSynthesisofNovel2-Tosyloxyphenylpyrans underGreenandConventionalConditionwithAnti-inflammatoryActivity Vol54 AhmedKhodairy, a AliM.Ali, a * MoustafaO.Aboelez, b andM.T.El-Wassimy a a DepartmentofOrganicChemistry,FacultyofScience,SohagUniversity,Sohag82524,Egypt b DepartmentofPharmaceuticalMedicinalChemistry,FacultyofPharmacy,SohagUniversity,Egypt *E-mail:elssan@yahoo.com AdditionalSupportingInformationmaybefoundintheonlineversionofthisarticle. ReceivedApril16,2016 DOI10.1002/jhet.2730 Publishedonline19July2016inWileyOnlineLibrary(wileyonlinelibrary.com). Amild,efficient,andenvironmentallygreenprotocolforthesynthesisof2-tosyloxyphenylpyran derivatives3-11viareactionof2-tosyloxybenzaldehyde(1)withmalononitrileandsomeketonicreagents inone-pot,threecomponentreactionwithinfewminutesunderstirringinmethanolinpresenceofammonium hydroxidesolutionorultrasonicirradiation.Ontheotherhand,thesameproducts3-11wereobtainedby traditionalmethod,ontreatmentof2-tosyloxybenzilidinemalononitrile(2)withthesameketonicreagents inrefluxingethanolinpresenceofTEA.2-Tosyloxyphenylpyranopyrazoles12and13wereobtainedvia treatmentofcompound1withmalononitrile,hydrazinehydrateorphenylhydrazineandethylacetoacetate, inone-pot,multicomponentreaction(MCRs).Thestructuresofthenewcompoundswereelucidatedbyele- mentalandspectralanalyses.Thenewlysynthesizedcompoundsshowedpromisinganti-inflammatoryactivity Read more

Efficient Protocol for the One-Pot Multicomponent Synthesis of Novel 2-Tosyloxyphenylpyrans and Schiff bases with Anti-inflammatory and Antioxidant Activities
1442One-PotMulticomponentSynthesisofNovel2-Tosyloxyphenylpyrans underGreenandConventionalConditionwithAnti-inflammatoryActivity Vol54 AhmedKhodairy, a AliM.Ali, a * MoustafaO.Aboelez, b andM.T.El-Wassimy a a DepartmentofOrganicChemistry,FacultyofScience,SohagUniversity,Sohag82524,Egypt b DepartmentofPharmaceuticalMedicinalChemistry,FacultyofPharmacy,SohagUniversity,Egypt *E-mail:elssan@yahoo.com AdditionalSupportingInformationmaybefoundintheonlineversionofthisarticle. ReceivedApril16,2016 DOI10.1002/jhet.2730 Publishedonline19July2016inWileyOnlineLibrary(wileyonlinelibrary.com). Amild,efficient,andenvironmentallygreenprotocolforthesynthesisof2-tosyloxyphenylpyran derivatives3-11viareactionof2-tosyloxybenzaldehyde(1)withmalononitrileandsomeketonicreagents inone-pot,threecomponentreactionwithinfewminutesunderstirringinmethanolinpresenceofammonium hydroxidesolutionorultrasonicirradiation.Ontheotherhand,thesameproducts3-11wereobtainedby traditionalmethod,ontreatmentof2-tosyloxybenzilidinemalononitrile(2)withthesameketonicreagents inrefluxingethanolinpresenceofTEA.2-Tosyloxyphenylpyranopyrazoles12and13wereobtainedvia treatmentofcompound1withmalononitrile,hydrazinehydrateorphenylhydrazineandethylacetoacetate, inone-pot,multicomponentreaction(MCRs).Thestructuresofthenewcompoundswereelucidatedbyele- mentalandspectralanalyses.Thenewlysynthesizedcompoundsshowedpromisinganti-inflammatoryactivity Read more