ghada_galal

Ghada Galal

Professor - Head of Tropical Medicine and Gastroenterology Department

Faculty of medicine

Address: Sohag, Egypt

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Publications Which contain the keyword: Rheumatoid Arthritis


The relationship of anti-cyclic citrullinated peptide (CCP) antibodies and rheumatoid factor with disease activity in patients with rheumatoid arthritis
Abstract Introduction: Autoantibodies in rheumatoid arthritis (RA) are useful both for diagnosis and prognosis. Anti-cyclic citrullinated peptide (CCP) antibodies have recently been shown to predict development of RA as well as poor outcome in early arthritis. Data on their role in established RA is limited. Aim of the work: To determine the frequency of anti-CCP and rheumatoid factor positivities and ... Read more

2018-12-25 21:20:25 Keywords Rheumatoid Arthritis, leptin, Disease activity (DAS28),
The relationship of serum leptin levels with disease activity in Egyptian patients with rheumatoid arthritis
Abstract Aim of the work: To investigate whether serum leptin levels are elevated in patients with rheumatoid arthritis (RA) and whether these levels correlate with disease activity. Patients and methods: A case-control study was made on 37 patients with RA and 34 healthy control subjects. The following values were assessed for each patient: erythrocyte sedimentation rate (ESR), C reactive protein ... Read more

2018-10-29 16:41:18 Keywords Rheumatoid Arthritis, adjuvant arthritis, eugenol,
Eugenol Ameliorates Freund’s Adjuvant Induced Arthritis in Male Rats
ABSTRACT BACKGROUND: Rheumatoid arthritis (RA) is a chronic relapsing autoimmune disorder. Eugenol, a main component of clove oil, possesses potent anti-inflammatory and antioxidant activity. Present investigation was designed to evaluate anti-arthritic potential of eugenol in Freund’s Complete Adjuvant (FCA) induced arthritis in male albino rats. MATERIALS AND METHODS: Thirty two male albino rats were used. Eight male rats were used ... Read more

2018-10-27 22:11:55 Keywords Flowcytometry, CD59, CD55, Rheumatoid Arthritis,
استخدام تقنية التدفق الخلوي لتقييم نسبة البروتينات المنظمة لعمل النظام المناعي المكمل علي خلايا الدم الطرفية في مرضي التهاب المفاصل الروماتويدي.
Abstract: Background: Inappropriate activation or blockage of inhibition of the complement system could cause tissue damage in autoimmune diseases particularly rheumatoid arthritis (RA). CD55 and CD59 are proteins with complement regulatory (Creg) properties that ensure cell and tissue integrity when this system is activated. Objective: The aim of this study was to evaluate the expression of CD55 and CD59 complement ... Read more

2018-10-28 17:09:05 Keywords eugenol, diabetes mellitus, Rheumatoid Arthritis,
Evaluation of the potential role of eugenol in induced arthritis and diabetes mellitus in rats
ABSTRACT BACKGROUND: Systemic inflammatory burden in rheumatoid arthritis (RA) has been shown to predispose to developing both insulin resistance and type 2 diabetes mellitus (DM). Polypharmacy with cumulative side effects are common problems met with in these medical situations of combined diseases. AIM OF THE WORK: the present study evaluates the potential role of eugenol as a natural product with ... Read more

Role of Serum Matrix Metalloproteinase-1 and Tumor Necrosis Factor- α in Rheumatoid Arthritis and Osteoarthritis
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by joint inflammation and destruction resulting in degradation of extracellular cartilage matrix. Osteoarthritis (OA) is also associated with degradation of molecular components of cartilage matrix with eventual loss of joint cartilage function. Matrix metalloproteinases (MMPs) are a family of proteinases modulated enzymes that play an important role in the pathogenesis ... Read more

2018-10-14 22:13:54 Keywords VITAMIN D, Rheumatoid Arthritis, DISEASE ACTIVITY,
The relationship of serum 25-hydroxyvitamin D levels with disease activity in upper Egyptian patients with rheumatoid arthritis
ABSTRACT Aim of the work: To assess the serum 25-hydroxyvitamin D concentrations [25(OH)D] and their relationship with parameters of disease activity in upper Egyptian patients with rheumatoid arthritis (RA). Patients and methods: A case-control study was made on 34 patients with RA and 34 healthy control subjects. The following values were assessed for each patient: erythrocyte sedimentation rate (ESR), C ... Read more

Is It the Age at Disease Onset or the Disease Radiological Severity That Affects Cervical Spine Involvement in Patients With Rheumatoid Arthritis?
_ABSTRACT _ BACK GROUND: Cervical spine involvement in patients with rheumatoid arthritis (RA) can cause pain and disability, with a variety of neurologic signs and symptoms. OBJECTIVES: To investigate the relationship between structural cervical spine involvement in patients with RA with the age at disease onset and the degree of radiologic severity of RA measured by Larsen scoring. PATIENTS AND ... Read more

2018-10-16 01:04:04 Keywords 28 joints, DAS, ultrasound, DAS, Ultrasound, Rheumatoid Arthritis,
Is It the Age at Disease Onset or the Disease Radiological Severity That Affects Cervical Spine Involvement in Patients With Rheumatoid Arthritis?
ABSTRACT BACkgROunD: Cervical spine involvement in patients with rheumatoid arthritis (RA) can cause pain and disability, with a variety of neurologic signs and symptoms. OBjeCTIveS: To investigate the relationship between structural cervical spine involvement in patients with RA with the age at disease onset and the degree of radiologic severity of RA measured by Larsen scoring. PATIenTS AnD meThODS: This ... Read more

2018-10-16 01:21:56 Keywords Rheumatoid Arthritis,
Assessment of Joint inflammatory activity in rheumatoid arthritis: a comparative study between clinical evaluation and musculoskeletal ultrasound
_ABSTRACT_ INTRODUCTION: Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by the development of synovitis, which damages cartilage, bone, ligaments, and tendons. US is available, noninvasive, and relatively inexpensive bedside imaging method with high patient acceptability. This technique is more sensitive and reproducible than clinical evaluation in assessing joint inflammation. Power Doppler (PD) US detect flow from small vessels ... Read more