amr_ali

Amr Abdelhamed Ali Yousef

Lecturer - Lecturer, Department of Dermatology, Venereology & Andrology

Faculty of medicine

Address: Faculty of Medicine, Sohag University.

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Publications Which contain the keyword: Aging


جيناتك ليست قدرك. Genes and the Environment: The Science of Epigenetics
At one time scientists believed that our DNA carry the key to preventing and reversing disease, but now we know that the environment and not our genes is the primary triggering of health and longevity. The science of epigenetics is explaning what we’ve long think about our biological destiny upside/ down. Although it remains that our DNA and our genetic ... Read more

2018-10-31 00:44:50 Keywords Aging, skin, nerve growth factor,
Age-associated decrease of the nerve growth factor protein expression in the human skin: preliminary findings
* AGE-ASSOCIATED DECREASE OF THE NERVE GROWTH FACTOR PROTEIN EXPRESSION IN THE HUMAN SKIN: PRELIMINARY FINDINGS.ADLY MA, ASSAF H, HUSSEIN MR. J DERMATOL SCI. 2006 JUN;42(3):268-71. Read more

2018-10-14 19:02:29 Keywords Aging, Apoptosis, autophagosome, melatonin, gastrocnemius, Sarcopenia,
The protective effect of melatonin against age-associated sarcopenia-dependent tubular aggregates formation, lactate depletion and mitochondrial changes
To gain insight into the mechanism of sarcopenia and the protective effect of melatonin, the gastrocnemius muscles of young (3-4 months), early-aged (12 months), and old-aged (24 months) wild type C57BL/6J female mice, were examined by magnetic resonance and microscopy. Locomotor activity, lactate production and nuclear apoptosis were also assessed. The results support the early onset of sarcopenia at 12 ... Read more

2018-10-14 09:05:19 Keywords Sarcopenia, Aging, CSA, Type II muscle fibers, Mitochondria,
Identification of morphological markers of sarcopenia at early stage of aging in skeletal muscle of mice
The gastrocnemiusmuscle (GM) of young (3months) and aged (12 months) femalewild-type C57/BL6 micewas examined by light and electron microscopy, looking for the presence of structural changes at early stage of the aging process.Morphometrical parameters including body and gastrocnemius weights, number and type ofmuscle fibers, cross section area (CSA), perimeter, and Feret's diameter of single muscle fiber,were measured.Moreover, lengths of the ... Read more

2018-10-14 17:37:04 Keywords Aging, Sarcopenia, Inflammaging, Innate immunity, melatonin,
Aging and Sarcopenia. Role of the innate immunity and melatonin therapy
La inflamación asociada al envejecimiento es un tipo de inflamación crónica, sistémica y asintomática que aparece como resultado de un aumento de la respuesta inmune innata con la edad. Los estímulos que dan lugar a este tipo de inflamación convergen en la activación de las vías moleculares de la inmunidad innata NF-kB y el inflamasoma NLRP3. La inflamación asociada al ... Read more

2018-09-25 19:32:46 Keywords pinealectom, somatotrophs, Aging,
Augmentation of age-related changes in somatotrophs after long term pinealectomy
The relationship between growth hormone producing cells in the pars distalis of the pituitary gland (somatotrophs) and the pineal gland function in rats is nearly not elucidated, particularly in the aspect of melatonin participation. The current study tested whether the life-long reduction of endogenous melatonin levels due to pinealcctomy would.influence the morphological and the ultra structural changes of somatotrophs as ... Read more

2018-09-19 15:34:32 Keywords Aging, angiogenesis, Oxidative stress, apoptosis.,
Oxidative Stress, Angiogenesis and Apoptosis in Relation to Aging
ABSTRACT Apoptosis and aging are complementary and cooperative processes that reduce cell proliferation and promote resistance to tumor development. Cellular levels of oxidative stress increase during physiological aging and tend to induce apoptosis, thereby influencing cellular and tissue aging and life span. Aim of study: is to determine the relationship between aging and apoptotic indices in the form of s-Fas ... Read more

Testosterone replacement alters the cell size in visceral fat but not in subcutaneous fat in hypogonadal aged male rats as a late-onset hypogonadism animal model.
BACKGROUND: Patients with late-onset hypogonadism (LOH) benefit from testosterone replacement by improvement in the parameters of the metabolic syndrome, but fat cell morphology in these patients is still unclear. This study aims to determine the effect of testosterone replacement on the morphology of fat cells in subcutaneous and visceral adipose tissue and on erectile function in hypogonadal aged male rats ... Read more