Urocortin and cytokines in gastric mucosa: Relationship to inflammatory activity before and after medical eradication of Helicobacter Pylori
BACKGROUND AND AIMS: There is a debate whether the majority of gastritis mucosal injury occurs as a direct effect of _H. pylori_ infection or as a result of immune cell damage from abundant mediators of inflammatory response. Recently, Urocortin (UCN) has emerged as a mediator of gastrointestinal (GI) responses to noxious stimuli. Interleukins-1β (IL-1β) and interleukin-10 (IL-10) may play important ... Read more