Abstract Introduction: Autoantibodies in rheumatoid arthritis (RA) are useful both for diagnosis and prognosis. Anti-cyclic citrullinated peptide (CCP) antibodies have recently been shown to predict development of RA as well as poor outcome in early arthritis. Data on their role in established RA is limited. Aim of the work: To determine the frequency of anti-CCP and rheumatoid factor positivities and ... Read more

ABSTRACT INTRODUCTION: Rheumatoid arthritis (RA) is an inflammatory autoimmune disease characterized by chronic joint inflammation and extra-articular manifestations culminating in permanent disability without early therapeutic interventions. Early accurate diagnosis and therefore treatment of rheumatoid arthritis (RA) has become increasingly important. AIM OF THE WORK: To compare the diagnostic power of anti-cyclic citrullinated peptide (ACCP) antibody to rheumatoid factor (RF) in ... Read more