ABSTRACT _Aim:_ to evaluate safety and efficacy of harmonic scalpel in closure/division of the cystic duct and artery, and bladder dissection in laparoscopic cholecystectomy as a single working instrument, with the use of two working trocars, compared with clip/cautery, three trocars technique. _Method:_ A prospective study included 160 patients with symptomatic gall stone disease were randomly assigned for laparoscopic cholecystectomy ... Read more