Expression of C-KIT Tyrosine Kinase Receptor, Epidermal Growth Factor, and p53 Proteins in the epithelial and mesenchymal cells of Hepatoblastoma: Preli.minary Findings
Background: Overexpression of receptor-type protein tyrosine kinases (PTKs) and alterations of p53 are well known events in neoplastic cells and are associated with an aggressive tumor phenotype. To date, our knowledge about PTKs and p53 expression in the neoplastic cells (epithelial and mesenchymal cells) of hepatoblastoma is incomplete. Objectives: This study tries to address this issue and test the hypothesis ... Read more