Initial State and Transition State Contributions to Reactivity Trends of Base-Catalyzed Hydrolysis of Some Nitro Chromen-2-One Derivatives
Base-catalyzed hydrolysis of 6-nitro-2H-chromen-2-one (NC) and 6-nitro-2H-chromen-2-one-3-carboxylic acid (NCC) in binary water/methanol and water/acetone mixtures were studied kinetically at 298 K. The changes in the activation barrier of the investigated compounds from water to water/methanol and water/acetone mixtures were estimated from the kinetic data. Solvent effects on the reactivity trends were analyzed into initial state and transition state components. These ... إقراء المزيد