Expression of Survivin, Bcl-xL and Bax in Laryngeal Squamous Cell Carcinoma; A Clinicopathological Study
ABSTRACT Laryngeal squamous cell carcinoma (SCC) is the most frequent tumor of head and neck region. Survivin (SVV) is one of the inhibitors of apoptosis which is over-expressed in almost all malignancies but rarely detected in normal differentiated adult tissues. Bcl-XL and Bax are members of a family of proteins that regulate apoptosis. In contrast to Bcl-XL that inhibits apoptosis ... Read more