eman_shalabi

Eman Muhammad Salah El-Deen Muhammad Shalabi

Professor - Professor Emeritus of Pathology

Faculty of medicine

Address: القوصية - محافظة أسيوط

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Publications Which contain the keyword: Cardiac

electrocardiographic changes in chronic hemodialysis children at sohag university hospital

2018-10-25 21:18:31 Keywords ECG, Cardiac, Hemodialysis,
electrocardiographic changes in chronic hemodialysis children at sohag university hospital
Abstract: Background: Cardiovascular disease is the leading cause of mortality among patients on chronic hemodialysis (HD). 30% of the deaths in these patients are due to cardiac arrest, death of unknown cause or cardiac arrhythmia. The increasing time of ventricular depolarization and repolarization, measured by QT interval duration on the electrocardiogram (ECG) at rest, has emerged as a predictor of ... Read more

Chronic adenosine receptor blockade with BG9928 attenuates cardiac and renal histopathology and improves diabetes in animals with the metabolic syndrome

2018-09-27 23:45:24 Keywords Diabetes , renal histopathology, Cardiac, adenosine receptor blockade,
Chronic adenosine receptor blockade with BG9928 attenuates cardiac and renal histopathology and improves diabetes in animals with the metabolic syndrome
PURPOSE: In animals and patients with left ventricular dysfunction, shortterm A1 adenosine receptor blockade causes diuresis/natriuresis without altering potassium excretion and, in contrast to loop diuretics, improves renal function. Blockade of the A2b adenosine receptor has an antidiabetic effect. The purpose of this study was to examine the long-term efficacy and safety of BG9928, a novel, orally active, and highly ... Read more

Dual A1/A2B Receptor Blockade Improves Cardiac and Renal Outcomes in a Rat Model of Heart Failure with Preserved Ejection Fraction

2018-09-09 13:13:38 Keywords Dual A1/A2B Receptor Blockade, Cardiac, renal, Rat, Heart Failure, Ejection Fraction,
Dual A1/A2B Receptor Blockade Improves Cardiac and Renal Outcomes in a Rat Model of Heart Failure with Preserved Ejection Fraction
Heart failure with preserved ejection fraction (HFpEF) is prevalent and often accompanied by the metabolic syndrome. Current treatment options are limited. Here we test the hypothesis that combined A1/A2B adenosine receptor blockade is beneficial in obese ZSF1 rats, an animal model of HFpEF with the metabolic syndrome. BG9928, a combined A1/A2B receptor antagonist, was administered orally (10 mg/kg/day) to obese ... Read more

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