abdelraheem_mohamed

عبدالرحيم محمد احمد محمود

مدرس -

كلية العلوم

العنوان: جامعة سوهاج - كلية العلوم - قسم الكيمياء

1

إعجاب

المنشورات و المؤلفات التي تحتوي علي الكلمة المفتاحية: phase transfer catalysis


2018-10-31 16:47:41 الكلمات المفتاحية PASS INET, fused pyridine, pyrrazole;, pyrimidine;, pyrrole, pyridine;, phase transfer catalysis,
Synthesis of Some New F used P yridines and Prediction their Biological Activity via PASS INET
A new series of fused heterocyclic compounds containing pyridine moieties were prepared via the reaction of 2-amino-6-(methylthio)-4-phenylpyridine-3,5-dicarbonitrile with some halo reagents, active methylenes, acetic anhydride, phenylisothiocyanate, hydrazine hydrate or thioacetamide. Accompanied with Predictions of the activity spectra of some selected compounds using PASS INET.at Pa > 70%, showing high probability of Atherosclerosis treatment, Antineoplastic, DNA intercalator, Protein kinase inhibitor and ... إقراء المزيد

2018-10-31 16:38:24 الكلمات المفتاحية thienopyridines, Pyridines, phase transfer catalysis,
Synthesis of Novel Fused Heterocycles Based on 6-Amino-4-phenyl-2-thioxo-1,2-dihydropyridine-3,5-dicarbonitrile
Under phase transfer catalysis conditions, 6‐amino‐4‐phenyl‐2‐thioxo‐1,2‐dihydropyridine‐3,5‐dicarbonitrile (1) was allowed to react with halo compounds, acrylonitrile, chloroacetyl chloride, ethyl cyanoacetate, formamide, triethylorthoformate, or formic acid to give new derivatives of fused pyridines 2–22, respectively. Acetylation of compound 1 using acetic anhydride afforded product 23, which in turn underwent intramolecular cyclization in pyridine to give the corresponding pyrido[2,3‐_d_]pyrimidine 24. إقراء المزيد

Synthesis of  Novel Coumarin Derivatives Based on 6-Aminocoumarin, Kinetic Inspection of  Base Hydrolysis and Spectrophotometric Tracer of  Intermediate Progress
The importance of 6-aminocoumarin, D-glucose, and ethyl cyanoacetate in pharmaceutical field was documented in literatures. Therefore, 6-aminocoumarin was reacted with single and double molarity of D-glucose forming Schiff’s base and bis-compound derivatives. Also, it was reacted with CS2 in phase transfer catalysis condition producing dithiocarbamate, which was used as an intermediate for the preparation of fused and polyfused derivatives. Additionally, ... إقراء المزيد

2018-09-18 22:04:33 الكلمات المفتاحية phase transfer catalysis,
Synthesis of Novel Fused Heterocycles Based on 6-Amino-4-phenyl-2-thioxo-1,2-dihydropyridine-3,5-dicarbonitrile
Under phase transfer catalysis conditions, 6‐amino‐4‐phenyl‐2‐thioxo‐1,2‐dihydropyridine‐3,5‐dicarbonitrile (1) was allowed to react with halo compounds, acrylonitrile, chloroacetyl chloride, ethyl cyanoacetate, formamide, triethylorthoformate, or formic acid to give new derivatives of fused pyridines 2–22, respectively. Acetylation of compound 1 using acetic anhydride afforded product 23, which in turn underwent intramolecular cyclization in pyridine to give the corresponding pyrido[2,3‐_d_]pyrimidine 24. إقراء المزيد

2018-09-18 21:57:39 الكلمات المفتاحية PASS INET, fused pyridine, pyrrazole, Pyrimidine, pyrrole, pyridine, phase transfer catalysis,
Synthesis  of  Some  New F used  P yridines  and  Prediction  their  Biological Activity via PASS INET
A new series of fused heterocyclic compounds containing pyridine moieties were prepared via the reaction of 2-amino-6-(methylthio)-4-phenylpyridine-3,5-dicarbonitrile with some halo reagents, active methylenes, acetic anhydride, phenylisothiocyanate, hydrazine hydrate or thioacetamide. Accompanied with Predictions of the activity spectra of some selected compounds using PASS INET.at Pa > 70%, showing high probability of Atherosclerosis treatment, Antineoplastic, DNA intercalator, Protein kinase inhibitor and ... إقراء المزيد