Synthesis of Novel Modified Guanidines: Reaction of Dicyandiamide with Amino Acids, Amides, and Amines in Aqueous Medium
Reaction of dicyandiamide with series of amino acids afforded guanidinyl pyrazolones 2–19, respectively. Although reaction of dicyandiamide with urea, acetamide, bezamide, allantion, p-aminobenzoic acid, sulphanilic acid, and adenine gave biguanides 20–26, respectively. All compounds have been characterized on the basis of IR and 1H-NMR. إقراء المزيد